Results 141 to 150 of about 257,500 (259)

Speed limit! [PDF]

British Journal of Psychiatry, 2013
openaire   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Speed limits and their effect on air pollution in Mexico City: A quasi-experimental study. [PDF]

Sci Total Environ
Texcalac-Sangrador JL, Pérez-Ferrer C, Quintero C, Prado Galbarro FJ, Yamada G, Gouveia N, Barrientos-Gutierrez T.   +6 more
europepmc   +1 more source

Fundamental Speed Limits to the Generation of Quantumness. [PDF]

Sci Rep, 2016
Jing J, Wu LA, Del Campo A.
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

An advanced real-time crash prediction framework for combined hard shoulder running and variable speed limits system using transformer. [PDF]

Sci Rep
Abdel-Aty M, Hasan T, Anik BMTH.
europepmc   +1 more source

Public attitudes to, and perceived impacts of 20mph (32km/h) speed limits in Edinburgh: an exploratory study using the Speed Limits Perceptions Survey (SLiPS).

Transp Res Part F Traffic Psychol Behav, 2022
europepmc   +1 more source

Assessing the Impact of Vehicle Speed Limits and Fleet Composition on Air Quality Near a School. [PDF]

Int J Environ Res Public Health, 2019
Tang J, McNabola A, Misstear B, Pilla F, Alam MS.   +4 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Speed Limits for Nonvesicular Intracellular Sterol Transport. [PDF]

Trends Biochem Sci, 2017
Dittman JS, Menon AK.
europepmc   +1 more source