Results 101 to 110 of about 152,644 (306)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Analysis of Determinants of the Speed of Adjustment to Target Capital Structure of Companies in Developing Economies

open access: yesКорпоративные финансы, 2019
The financial stability of a company, along with its operational effectiveness, depend on whether the company endeavours to optimise its capital structure, and the speed at which it can do so.
Eugene Nivorozhkin, Eugeniu Kireu
doaj   +1 more source

Firm Characteristics, Economic Conditions and Capital Structure Adjustment [PDF]

open access: yes
We use a dynamic framework and panel methodology to investigate the determinants of a firms’ time-varying capital structure. Our sample comprises 706 European firms from France, Germany, Italy and the U.K. over the period from 1983 to 2002.
Wolfgang Drobetz   +2 more
core  

Testing Target-Adjustment and Pecking Order Models of Capital Structure and Estimating Speed of Adjustment

open access: yes, 2017
This article examines the explanation power of the pecking order and target adjustment models on 148 Borsa Istanbul (BIST) firms' capital structure over the period of 2005 to 2015.
Levent Ataünal, Aslı Aybars
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Financial constraints and the speed of adjustment of trade credit extension: the case in an emerging country

open access: yesCogent Economics & Finance
Using a sample of listed non-financial firms in Vietnam from 2010 to 2022, this study investigates the dynamics of trade receivables by analyzing the speed of adjustment toward target levels, with particular attention to the moderating effects of Covid ...
Liem Nguyen, Ly Huynh, Thu Luu
doaj   +1 more source

Patterns of Capital Structure Adjustment by Listing Type: Evidence from European Firms [PDF]

open access: yesEurasian Journal of Business and Economics, 2012
This study analyzed the questions of whether capital structure adjustment in European firms differed by listing type and by current debt ratio. Major issues are concerned with (1) the adjustment speed toward target debt ratio and (2) the length of the ...
Joshua Seungwook BAHNG
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

LABOR ADJUSTMENT DYNAMICS: AN APPLICATION OF SYSTEM GMM [PDF]

open access: yes
This paper analyzes the dynamics of the Portuguese labor market using micro data: implications of adjustment costs to input factor adjustment throughout the business cycle are discussed; the current situation of the Portuguese labor market is reviewed ...
Pedro M. Esperança
core  

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