TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Accurate prediction of density, viscosity, and speed of sound in aqueous aliphatic biogenic polyamine solutions using data-driven modeling. [PDF]
Mohammad SI +9 more
europepmc +1 more source
A Dual-Path Pulse-Echo Instrument for Liquid-Phase Speed of Sound and Measurements on <i>p</i>-Xylene and Four Halogenated-Olefin Refrigerants [R1234yf, R1234ze(E), R1233zd(E), and R1336mzz(Z)]. [PDF]
McLinden MO, Perkins RA.
europepmc +1 more source
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen +11 more
wiley +1 more source
Speed of sound and shear wave speed for calf soft tissue composition and nonlinearity assessment. [PDF]
Korta Martiartu N +5 more
europepmc +1 more source
ABSTRACT Mechanophores with mechanochromic properties have attracted significant attention as force‐responsive materials for structural sensing. However, their applications remain mainly limited to qualitative force visualization, as direct and quantitative extraction of mechanical parameters such as stress and strain from mechanochromic responses has ...
Seungo Baek +8 more
wiley +1 more source
Uncertainty estimation for trust attribution to speed-of-sound reconstruction with variational networks. [PDF]
Laguna S +6 more
europepmc +1 more source
Quantification of immobilization-induced changes in human calf muscle using speed-of-sound ultrasound: An observational pilot study. [PDF]
Ruby L +6 more
europepmc +1 more source
Ab Initio Thermoelectric Transport Calculations of Alloyed Half‐Heuslers
The effect of alloying on the electronic transport of half‐Heusler thermoelectric materials is explored using a fully ab initio approach. A novel method is developed that combines calculations of alloyed supercells with Boltzmann transport, considering the full energy and momentum dependent scattering processes from first principles extracted ...
Ankit Kumar +2 more
wiley +1 more source
Speed of sound for understanding metals in extreme environments. [PDF]
Rasmussen EG, Wilthan B.
europepmc +1 more source

