Results 161 to 170 of about 2,323,356 (342)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Calculated Hovering Helicopter Flight Dynamics with a Circulation Controlled Rotor [PDF]
The influence of the rotor blowing coefficient on the calculated roots of the longitudinal and lateral motion was examined for a range of values of the rotor lift and the blade flap frequency.
Chopra, I., Johnson, W.
core +1 more source
A High- Speed LFSR Design by the Application of Sample Period Reduction Technique for BCH Encoder
, 2014 Iosr Journals +4 more
openalex +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Study on the Performance of Hydraulic Reduction Turbine by Varying the Blade Number
Shiyou jixie, 2017 The idle speed and the working speed of the turbo-shaft could be greatly reduced by incorporating a certain number of hydraulic reduction turbines into the turbo-drill.With the NUMECA software,the three-dimensional stator and rotor model with different ...
Tan Chunfei +4 more
doaj
Survival Model of Drivers’ Speed Reduction Time at Bicycle Crossroads: A Driving Simulator Study [PDF]
, 2018 Francesco Bella, Manuel Silvestri
openalex +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Local ship speed reduction effect on black carbon emissions measured at remote marine station
, 2023 Mikko Heikkilä +3 more
openalex +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source