Results 181 to 190 of about 1,157,151 (303)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Optimization of constant-speed control algorithm for high-speed EMUs

机车电传动
Constant-speed control is deemed one of the core control functions for high speed EMUs, with accuracy being crucial for ensuring smooth operation. Given the complex operational environments of trains, ensuring the accuracy of constant-speed control for ...
XIONG Yan, ZHOU Shangru, XU Qing, HUANG He   +3 more
doaj  

A sensorimotor instability drives a locomotor transition during fish development. [PDF]

Sci Adv
Coraggioso M, Demarchi L, Wong R, Dichio V, Chaumeton C, Panier T, Morvan-Dubois G, Goodhill GJ, Bormuth V, Debrégeas G.   +9 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Host genomic regulation of ileal Bradyrhizobium abundance modulates eating speed and fat metabolism in birds: a causal mechanism study. [PDF]

J Anim Sci Biotechnol
Zhao Y, Zhai S, Wang P, Yang W, Liu X, Dai Y, Li C, Liu F, Yang N, Yan W.   +9 more
europepmc   +1 more source

The speed regulation of water wheels．

The speed regulation of water wheels．
種別 ...
openaire  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

PSO-optimized electronic load controller with intelligent energy recovery for self-excited induction generator based micro-hydro systems. [PDF]

Sci Rep
Sinha S, Rajak MK, Pudur R.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Faster fowl fall frequently: speed and force regulation during turning maneuvers by guinea fowl on high and low friction terrains. [PDF]

J Exp Biol
Goldsmith H, Hall J, Daley MA.
europepmc   +1 more source