Results 51 to 60 of about 290,168 (264)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Fuzzy Control of Three-Phase Induction Motor Using Mitsubishi PLC: Experimental Study

open access: yesJurnal Nasional Teknik Elektro dan Teknologi Informasi
Three-phase induction motors are extensively deployed in industrial automation due to their robustness, simplicity, and efficiency. Nevertheless, maintaining speed stability under dynamically varying loads remains a significant control challenge.
Nanang Rohadi, Liu Kin Men, Akik Hidayat
doaj   +1 more source

A Novel Motor-Speed-Regulation Method

open access: yesMATEC Web of Conferences, 2016
The traditional doubly-fed motor has less reliability because it needs carbon brushes and sliding rings which are not highly reliable. The brushless doubly-fed machine costs a lot for its framework requires special designing and processing.
Huang Zhou, Xu Zheng Wang
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Designing UAV Charging Framework for Forest Area with Microgrid

open access: yesEnergies
Unmanned aerial vehicles (UAVs) are suitable for forest fire monitoring, which is critical to prevent unexpected hazards. However, a lack of charging measures is the bottleneck restricting the development of surveillance drones in forest areas.
Ming Yu
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

SPEED AND CAR TRAFFIC REGULATION IN URBAN AREAS

open access: yesIATSS Research, 2003
Improvements in individual mobility conditions for drivers in the Paris conurbation (higher speed and lower cost of individual mobility) have contributed to the reduction of urban area density and have led to dominant use of the car and a dramatic ...
Marie-Hélène MASSOT
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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