Results 61 to 70 of about 1,890 (168)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

What is sent to spell-out is phases, not phasal complements

open access: yesLinguistica, 2016
An appealing property of the phase theory is that it is relevant to many phenomena, i.e. many domain-based mechanisms are stated in terms of phases.
Željko Bošković
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

ТРАДИЦІЙНІ МЕТОДИ ЛІКУВАННЯ В УКРАЇНЦІВ ТА РУМУНІВ БУКОВИНИ У ДРУКОВАНИХ МАТЕРІАЛАХ ТА АРХІВНИХ ДЖЕРЕЛАХ XVIII – ХХ СТ. / Traditional Methods of Treatment of Ukrainian and Rumanian of Bukovina’s written materials and archival sources XVIII - XX centuries.

open access: yesАктуальні питання суспільних наук та історії медицини, 2014
Antoniy Moysey. Traditional Methods of Treat- ment of Ukrainian and Rumanian of Bukovina’s written materials and archival sources XVIII - XX centuries The article presents the results of studies of folk medical practices in the XVIII – XX ...
Мойсей Антоній
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Evaluating Automatic Detection of Misspellings in German [PDF]

open access: yesLanguage Learning and Technology, 2008
his study investigates the performance of a spell checker designed for native writers on misspellings made by second language (L2) learners. It addresses two research questions: 1) What is the correction rate of a generic spell checker for L2 ...
Anne Rimrott, Trude Heift
doaj  

Marvin Luke's Blackout Spell

open access: yesMedEdPORTAL, 2007
This is a biochemistry problem-based learning (PBL) case suitable for either first-or second-year medical students. The patient is a 59-year-old black male who suffers an acute myocardial infarction. His total cholesterol and low-density lipoprotein (LDL)
Marshall Anderson
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

The union spell-out principle

open access: yesNordlyd: Tromsø University Working Papers on Language & Linguistics, 2009
This paper argues that grammar has a union spell-out principle that dictates that contiguous heads be spelled out by a single morpheme or phrase if there exists a morpheme or phrase in the lexicon with a collection of the features of the contiguous ...
Peter Kinyua Muriungi
doaj   +1 more source

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