The structural validity of the Danish version of the Oxford Knee Score is not substantiated using Rasch analysis and confirmatory factor analysis. [PDF]
Hansen CF +4 more
europepmc +1 more source
Additive and Partially Dominant Effects from Genomic Variation Contribute to Rice Heterosis
Additive and partially dominant effects, namely at mid‐parent levels or values between mid‐parent and parental levels, respectively, are the predominant inheritance patterns of heterosis‐associated molecules. These two genetic effects contribute to heterosis of agronomic traits in both rice and maize, as well as biomass heterosis in Arabidopsis ...
Zhiwu Dan +8 more
wiley +1 more source
Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao +11 more
wiley +1 more source
Exploring the determinants of Suicide among Married Women in Chitral, Khyber-Pakhtunkhwa, Pakistan. [PDF]
Hussain J, Sajjad S, Hussain K.
europepmc +1 more source
Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka +9 more
wiley +1 more source
Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank. [PDF]
Fonseca N +11 more
europepmc +1 more source
Integrating interpretable machine learning with the fixed‐potential method reveals a novel mechanism: the catalytic activity of the electrochemical nitrogen reduction reaction is governed by partial charge transfer, induced by variations in the intermediate potential of zero charge under constant potential.
Yufei Xue +6 more
wiley +1 more source
The Impact of a Health Coaching App on the Subjective Well-Being of Individuals With Multimorbidity: Mixed Methods Study. [PDF]
Symes I, Burton A, Mercado D, Bu F.
europepmc +1 more source

