Results 201 to 210 of about 316,099 (294)

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

Structural Variation Sequencing of 26 Amniotic Fluid Samples With Partial Gene Duplications and Postnatal Follow‐Up of the Fetuses

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objectives Partial gene duplications (PGDups) are a significant contributor to genetic disease. The precise genomic location and structure of PGDups are often unresolved using conventional methods, so prenatal diagnosis for PGDups is challenging, especially without ultrasound abnormalities.
Shengfang Qin   +10 more
wiley   +1 more source

Optimal irradiation parameters for the development of the sterile insect technique in the seedcorn maggot Delia platura (Diptera: Anthomyiidae)

open access: yesPest Management Science, EarlyView.
X‐ray irradiation of Delia platura pupae showed that 20 Gy induces high sterility while maintaining male quality and competitiveness, establishing optimal parameters for sterile insect technique implementation in North America. Abstract BACKGROUND The seedcorn maggot, Delia platura Meigen (Diptera: Anthomyiidae), is a sporadic but economically ...
Anne‐Marie Fortier   +3 more
wiley   +1 more source

Monitoring the fate of paternal mitochondria and their elimination in rice zygotes. [PDF]

open access: yesPlant Physiol
Aini H   +8 more
europepmc   +1 more source

Mating history shapes Wolbachia‐induced cytoplasmic incompatibility and female fitness in an insect pest

open access: yesPest Management Science, EarlyView.
Mating order and remating of females by males with different endosymbiont associations strongly shape Wolbachia‐induced cytoplasmic incompatibility, female fitness and offspring sex ratio. An incompatible first mating was weakly affected if followed by a compatible mating and vice versa, indicating strong first‐male sperm precedence with consequences ...
Amir H. Tourani   +4 more
wiley   +1 more source

Towards the Establishment of a Sea Urchin Sperm Biobank: Key Challenges and Opportunities for the Conservation and Sustainable Aquaculture of <i>Paracentrotus lividus</i>. [PDF]

open access: yesAnimals (Basel)
Antenucci E   +13 more
europepmc   +1 more source

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