Results 261 to 270 of about 1,104,726 (307)
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source
Advanced Science, Volume 13, Issue 5, 27 January 2026.Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu +6 more
wiley +1 more source
Global Diversification Rates of Ferns Across Spatial and Climatic Gradients
Advanced Science, Volume 13, Issue 3, 14 January 2026.Diversification rates of fern genera across the phylogeny. Abstract Geographic patterns of diversity in any group of plants are the result of the interplay of environmental conditions and the evolutionary dynamics of the respective plant group. Here, the geographic distribution of current mean diversification rates (MDR) is explored at the genus level ...
Hong Qian, Michael Kessler, Shenhua Qian
wiley +1 more source
Soft Micromanipulation Robot for Real‐Time Adaptive Multimodal Operation
Advanced Science, Volume 13, Issue 2, 9 January 2026.This manuscript proposes a soft micromanipulator robot (SMR) for “full‐angle” precision biomedical operations. Bio‐inspired SMR achieves omnidirectional motion, micrometer precision, and multimodal capabilities including aspiration, transfer, rotation, assembly, injection, and cutting.
Zhuowei Li +8 more
wiley +1 more source
Advanced Science, Volume 13, Issue 1, 5 January 2026.CBTi‐seq is reported, leveraging Tn5 transposase‐mediated molecular assembly of combinatorial barcodes and UMIs for high‐resolution multiplexed sequencing of the full‐length transcriptome in single cells. This approach achieves molecular resolution by end‐to‐end sequencing, enabling reconstruction of splice variants and accurate quantification of ...
Liyong He +14 more
wiley +1 more source
“What is a fish without a river?” Conservation Translocation of a Highly Threatened Cyprinid
Aquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 1, January 2026.ABSTRACT Conservation translocations are essential for reversing biodiversity loss. Here, we report a translocation initiative on the endangered Evrotas chub (Squalius keadicus) to re‐establish it in the Vassilopotamos River, within its historical range in Greece.
Leonidas Vardakas +4 more
wiley +1 more source
BioEssays, Volume 48, Issue 1, January 2026.TDP‐43 hyperphosphorylation occurs in neurodegenerative diseases, however, it is not a driver of TDP‐43 aggregation, but enhances TDP‐43 solubility, suggesting that TDP‐43 hyperphosphorylation is protective. Toxicity may arise from a broader phosphorylation‐driven cellular pathway disruption.
Simone Mosna, Dorothee Dormann
wiley +1 more source
New Phytologist, Volume 249, Issue 4, Page 1580-1591, February 2026.
Ana M. Florez‐Rueda +5 more
wiley +1 more source
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Encyclopedia of Evolutionary Psychological Science, 2016
A.G. Rowley, J.L. Fitzpatrick
semanticscholar +5 more sources
A.G. Rowley, J.L. Fitzpatrick
semanticscholar +5 more sources