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Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu, Kaifeng Niu, Qingran Kong, Shaorong Gao   +3 more
wiley   +1 more source

Identification of a Novel Biallelic CFAP119 Variant in an Infertile Man with Asthenoteratozoospermia

The World Journal of Men's Health
Purpose: Infertility affects approximately 10% to 20% of couples globally, with male factors contributing to nearly 50% of infertility cases. Among these, represents a severe form of male infertility, though its etiology remains largely unknown ...
Jun Ma, Tiechao Ruan, Chuan Jiang, Xiang Wang, Yingteng Zhang, Yunchuan Tian, Xinyao Tang, Yihong Yang, Ying Shen   +8 more
doaj   +1 more source

Predictive performance of Fetal Medicine Foundation first‐trimester screening algorithm for pre‐eclampsia according to conception mode

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 6, Page 806-814, June 2026.
ABSTRACT Objective To investigate the incidence of pre‐eclampsia (PE) and the predictive performance of the Fetal Medicine Foundation (FMF) first‐trimester PE screening algorithm across pregnancies conceived using assisted reproductive technology (ART), after ovulation induction (OI) and through spontaneous conception (SC).
A. S. L. Kjaer, I. Riishede, L. Rode, R. B. Jensen, K. Pihl, L. Sperling, M. Overgaard, N. G. Pedersen, A. C. Roslev, P. Sandager, A. Tabor, A. Pinborg, C. K. Ekelund, the PRESIDE Study Group, P. Nørgaard, C. Vedel, H. Skov, S. R. Wagner, H. J. Zingenberg, M. R. Andersen, L. Bathum, T. Hilling, C. S. Knudsen, F. S. Jørgensen   +23 more
wiley   +1 more source

Association Between Third‐Stage Duration and Postpartum Hemorrhage in Women With Retained Placenta

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 6, June 2026.
ABSTRACT Aim To examine the association between third‐stage duration and total blood loss in women with retained placenta. Secondary analyses were performed to explore clinical factors associated with postpartum hemorrhage (PPH). Methods This retrospective cohort study included women with singleton vaginal deliveries at ≥ 22 gestational weeks between ...
Fumika Shimizu, Tatsuya Arakaki, Hiroko Takita, Yuka Yamashita, Mayumi Kaneko, Ryu Matsuoka, Akihiko Sekizawa   +6 more
wiley   +1 more source

Immunomodulatory Role of Natural Progesterone in Pregnancy: A Review

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 6, June 2026.
ABSTRACT Aim Pregnancy complications such as miscarriage, preterm birth (PTB), and luteal phase defects (LPD) are significant reproductive health issues globally, with both physical and psychological implications. This review aims to examine the role of natural progesterone in pregnancy‐related disorders, specifically threatened and recurrent ...
Prakash Mehta, Hemant Deshpande, Anjali Deshpande, Reshma Quadros, Shruti Dharmadhikari, Chintan Khandhedia, Gaurav Puppalwar, Amey Mane, Suyog Mehta   +8 more
wiley   +1 more source

Evolution of intracytoplasmic sperm injection: From initial challenges to wider applications

Reproductive Medicine and Biology
Background In vitro fertilization (IVF) has revolutionized infertility treatment. Nevertheless, male infertility requires more effective solutions. In 1992, the first‐ever case of human birth via intracytoplasmic sperm injection (ICSI) was reported. ICSI
Yoshimasa Asada
doaj   +1 more source

First live birth after in vitro fertilization in a woman with Alström syndrome: a case report

Frontiers in Reproductive Health
PurposeAlström syndrome (AS) is an extremely rare, autosomal recessive genetic disorder. Fertility implications are particularly relevant for women affected by AS, and no cases of patients achieving pregnancy and live birth with in vitro fertilization ...
Andrea Roberto Carosso, Marco Carosso, Alberto Revelli, Stefano Canosa, Luca Marozio, Gianluca Gennarelli, Pietro Maffei, Serena Ditaranto, Chiara Benedetto   +8 more
doaj   +1 more source

Assisted reproductive technology in Japan: A summary report for 2021 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology

Reproductive Medicine and Biology
Purpose The Japan Society of Obstetrics and Gynecology (JSOG) registry gathers comprehensive data from registered assisted reproductive technology (ART) facilities in Japan. Herein, we report 2021 ART cycle characteristics and outcomes.
Yukiko Katagiri, Seung Chik Jwa, Akira Kuwahara, Takeshi Iwasa, Masanori On, Keiichi Kato, Hiroshi Kishi, Yoshimitsu Kuwabara, Fuminori Taniguchi, Miyuki Harada, Akira Iwase, Yutaka Osuga   +11 more
doaj   +1 more source

Impact of Varicocele Repair on Assisted Reproductive Technique Outcomes in Infertile Men: A Systematic Review and Meta-Analysis

The World Journal of Men's Health
Purpose: In this systematic review and meta-analysis, we investigated assisted reproductive technology (ART) success in infertile men with clinical varicocele and abnormal semen parameters who underwent varicocele repair (VR) before the ART procedure ...
Ayad Palani, Rossella Cannarella, Ramadan Saleh, Gianmaria Salvio, Ahmed M. Harraz, Andrea Crafa, Fahmi Bahar, Kadir Bocu, Naveen Kumar, Priyank Kothari, Germar-Michael Pinggera, Selahittin Cayan, Giovanni M. Colpi, Widi Atmoko, Rupin Shah, Ashok Agarwal   +15 more
doaj   +1 more source

Assisted reproductive technology in Japan: A summary report for 2022 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology

Reproductive Medicine and Biology
Purpose This descriptive analysis evaluated the 2022 assisted reproductive technology (ART) data collected by the Japan Society of Obstetrics and Gynecology registry.
Yukiko Katagiri, Seung Chik Jwa, Akira Kuwahara, Takeshi Iwasa, Masanori Ono, Keiichi Kato, Hiroshi Kishi, Yoshimitsu Kuwabara, Fuminori Taniguchi, Miyuki Harada, Akira Iwase, Norihiro Sugino   +11 more
doaj   +1 more source