Results 121 to 130 of about 66,025 (308)

Viscosity of concentrated mRNA solutions: Implications for downstream processing

Biotechnology Progress, EarlyView.
Abstract Messenger RNA (mRNA) therapeutics can be used to protect against infectious disease and for the treatment of cancers and genetic disorders. In order to obtain the desired therapeutic dosage, it is necessary to concentrate the mRNA to levels where the viscosity of the mRNA solutions can become significant.
Amin Javidanbardan, Fatemeh Najafi, Ziqiao Wang, Andrew L. Zydney   +3 more
wiley   +1 more source

Validation of a method for measuring sperm quality and quantity in reproductive toxicity tests with pair-breeding male fathead minnows (Pimephales promelas) [PDF]

, 2009
This article originally appeared in the ILAR e-Journal. It is reprinted with permission from the ILAR Journal, Institute for Laboratory Animal Research, National Research Council, Washington DC (www.nationalacademies.org/ilar).The fathead minnow ...
Hala, D, Holt, WV, Jobling, S, Van Look, K   +3 more
core  

Melatonin production improves Senegalese sole sperm motility at night, but fails as a supplement during cryopreservation [PDF]

Melatonin is a powerful antioxidant present in fish seminal plasma. This study aimed to understand melatonin's endogenous and exogenous effects on first-generation Senegalese sole sperm quality for sperm management applications.
Félix de Azeredo Pinto e Melo, Francisca, Oliveira, Catarina, Cabrita, Elsa, Ferrão, Leonor, Gallego, Victor   +4 more
core   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

The mu (µ) and delta (δ) opioid receptors modulate boar sperm motility [PDF]

, 2016
Endogenous and exogenous opioids modulate reproductive functions in target cells via opioid receptors (µ, δ, and κ). Sperm motility is a metric of gamete functionality, and serves as a suitable parameter for in vitro drug-induced toxicity assays.
Alejandro Vicente‐Carrillo, Manuel Álvarez‐Rodríguez, Rodriguez-Martinez, Heriberto, Álvarez Rodríguez, Manuel, Vicente Carrillo, Alejandro,, Heriberto Rodríguez‐Martínez, Rodriguez-Martinez, Heriberto,, Alvarez-Rodriguez, Manuel, Alvarez-Rodriguez, Manuel,, Rodríguez Martínez, Heriberto, Vicente Carrillo, Alejandro   +10 more
core   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

Embryonic development of the Mediterranean starfish Hacelia attenuata

Developmental Dynamics, EarlyView.
Abstract Background Starfish play essential ecological roles as predators and ecosystem regulators; however, detailed developmental descriptions exist for only a handful of species, none of which are from the Mediterranean Sea. Results In this study, we provide the first full account of the development of the Mediterranean starfish Hacelia attenuata ...
Silvia Caballero‐Mancebo, Laurent Gilletta, Janet Chenevert, Stefania Castagnetti   +3 more
wiley   +1 more source

Sperm motility in chronic bacterial prostatitis [PDF]

, 2015
Background: Male infertility is 40% couples' problem in conceiving a child. One of the causes of male infertility that has not studied yet is chronic bacterial prostatitis (CBP).
Dicky Moch Rizal, Dicky Moch Rizal
core  

A shining starlet: Nematostella vectensis as a model for developmental, regenerative, and comparative biology

Developmental Dynamics, EarlyView.
Abstract The sea anemone, Nematostella vectensis, has been used as a model organism in developmental biology studies for many years. This estuarine species has the notable capacity to regenerate its full body plan from small pieces throughout life. Nematostella have been described as having a great degree of cellular plasticity.
Patrick A. Lewis, Zachary Horowitz, Michael Shribak, Karen Echeverri   +3 more
wiley   +1 more source

Age, embryo donor status, and insemination with chilled semen all predispose to persistent breeding‐induced endometritis in warmblood mares

Equine Veterinary Journal, EarlyView.
Abstract Background Persistent breeding‐induced endometritis (PBIE) is a common reason for mares failing to establish pregnancy. Objective To examine the hypothesis that advancing mare age and embryo donor status predispose to PBIE and compromise fertility.
Tom Stout, Rik Serrarens, Bart Leemans, Anthony Claes   +3 more
wiley   +1 more source