Results 221 to 230 of about 66,025 (308)

Triclocarban impacts human sperm motility by inhibiting glycolysis and oxidative phosphorylation. [PDF]

Asian J Androl
Fu LL, Wang WZ, Feng Y, Chen F, Liu B, Huang L, Zhang LY, Chen L.   +7 more
europepmc   +1 more source

Sexual Safety Signals of Common Antidiabetic Drugs: Insights From FAERS Disproportionality Analysis

Andrology, EarlyView.
ABSTRACT Background Erectile dysfunction is a prevalent and distressing complication of diabetes mellitus that markedly affects quality of life in male patients. Although the role of diabetes in erectile dysfunction is well‐established, potential drug‐induced sexual dysfunction associated with commonly prescribed antidiabetic medications remains ...
Shan Lin, Xuefeng Ding, Xin Dang, Qingyuan Zhan   +3 more
wiley   +1 more source

Targeting SKAP2 restores sperm motility and morphology through modulating mitochondrial organization and cytoskeletal remodeling. [PDF]

Signal Transduct Target Ther
Gan S, Yin L, Zhou J, Li S, Zhou S, Yang X, Liu R, Fan X, Li Y, Yao Z, Chen J, Hu P, Xiong W, Yuan Y, Wen Y, Li Y, Jin G, Sheng J, Gao Y, Huang H, Zhang C.   +20 more
europepmc   +1 more source

Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +2 more
wiley   +1 more source

Erratum: [Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility <i>in vitro</i>. [PDF]

Exp Ther Med
Wang H, Chen T, Chen Y, Luo T, Tan B, Chen H, Xin H.   +6 more
europepmc   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben, Anne Prinsen, Laetitia de Kort, Jetske van Breda   +3 more
wiley   +1 more source

Glycerol Kinase 2 as a Metabolic Sentinel for Human Sperm Motility and Male Fertility. [PDF]

Biomolecules
Oliveira JS, Moreira RJ, Martins AD, Alves MG, Oliveira PF.   +4 more
europepmc   +1 more source

Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice

Andrology, EarlyView.
ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik, Jessica M. Snyder, Haley A. Martin, John K. Amory   +3 more
wiley   +1 more source

Proximity labeling of axonemal protein CFAP91 identifies EFCAB5 that regulates sperm motility. [PDF]

Nat Commun
Wang H, Shimada K, Pham AH, Oyama Y, Kamoshita M, Kobayashi H, Oura S, Yabuta N, Ikawa M, Miyata H.   +9 more
europepmc   +1 more source

Improvement of Mouse Spermatozoa Freezing at ‐80°C With Ascorbic Acid 2‐Glucoside at Thawing Phase

Andrology, EarlyView.
ABSTRACT Background Sperm cryopreservation is the most common method to maintain a great number of mutant mouse lines. However, the use of liquid nitrogen (LN2) for freezing presents considerable problems in terms of cost, safety, and accessibility. For this reason, the storage of semen samples at ‐80° in ultra‐freezers has been increasingly used in ...
Alessia Paradiso, Renata Paoletti, Simone Cassetti, Nicola Bernabò, Barbara Barboni, Marcello Raspa, Ferdinando Scavizzi   +6 more
wiley   +1 more source