Results 91 to 100 of about 17,497 (237)

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Cell cycle and age-related modulations of mouse chromosome stiffness

eLife
Chromosome structure is complex, and many aspects of chromosome organization are still not understood. Measuring the stiffness of chromosomes offers valuable insight into their structural properties.
Ning Liu, Wenan Qiang, Philip W Jordan, John F Marko, Huanyu Qiao   +4 more
doaj   +1 more source

Live-cell Imaging and Quantitative Analysis of Meiotic Divisions in Caenorhabditis elegans Males

Bio-Protocol, 2020
Live-imaging of meiotic cell division has been performed in extracted spermatocytes of a number of species using phase-contrast microscopy. For the nematode Caenorhabditis elegans, removal of spermatocytes from gonads has damaging effects, as most of the
Gunar Fabig, Falko Löffler, Christian Götze, Thomas Müller-Reichert   +3 more
doaj   +1 more source

Age Effects on Lactic- and Malic-Acid Dehydrogenases in C57BL/6 Mouse Testes [PDF]

, 1970
Author Institution: Department of Biological Sciences, Kent State University, Kent, Ohio 44240There is evidence that lactic-acid-dehydrogenase (LDH) and malic-acid-dehydrogenase (MDH) activities vary with age in several mammalian organs. This study shows
Burich, Raymond L., Ewing, Keith L.
core  

Regulation of Centromere Localization of the Drosophila Shugoshin MEI-S332 and Sister-Chromatid Cohesion in Meiosis [PDF]

, 2014
The Shugoshin (Sgo) protein family helps to ensure proper chromosome segregation by protecting cohesion at the centromere by preventing cleavage of the cohesin complex. Some Sgo proteins also influence other aspects of kinetochore-microtubule attachments.
Clarke, A., Kashevsky, Helena, Nogueira, C., Orr-Weaver, Terry, Pinto, Belinda Sophia   +4 more
core   +1 more source

Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +2 more
wiley   +1 more source

Propylthiouracil-induced hypothyroidism delays apoptosis during the first wave of spermatogenesis

Biological Research, 2011
Mammalian germ cell apoptosis plays a key role in controlling the correct number of germ cells supported by Sertoli cells during the first wave of spermatogenesis in mammalian puberty.
Doris Silva, Carlos Lizama, Verónica Tapia, Ricardo D Moreno   +3 more
doaj  

The Germline Linker Histone dBigH1 and the Translational Regulator Bam Form a Repressor Loop Essential for Male Germ Stem Cell Differentiation

Cell Reports, 2017
Drosophila spermatogenesis constitutes a paradigmatic system to study maintenance, proliferation, and differentiation of adult stem cell lineages.
Albert Carbonell, Salvador Pérez-Montero, Paula Climent-Cantó, Oscar Reina, Fernando Azorín   +4 more
doaj   +1 more source

Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice

Andrology, EarlyView.
ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik, Jessica M. Snyder, Haley A. Martin, John K. Amory   +3 more
wiley   +1 more source

Revue des connaissances actuelles sur la cytogénétique des glossines (Diptera) [PDF]

, 1973
Les caryotypes de douze espèces de Glossines ont été décrits par différents auteurs, au cours des six dernières années. Toutefois, parmi celles-ci, sept espèces seulement ont été relativement bien étudiées: deux espèces du groupe palpalis (G.
Itard, Jacques
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