RNF187 mediates the polyubiquitination and subsequent degradation of WDR77, reduces H4R3me2s catalysed by the WDR77/PRMT5 complex, and derepresses the transcription of EGR1, thereby promoting the proliferation and migration of human SSCs. ABSTRACT The E3 ubiquitin ligase RNF187, also known as RING domain AP1 coactivator‐1, is a member of the RING ...
Haoyue Hu+12 more
wiley +1 more source
Histone hyperacetylation disrupts spermatogonial stem cells homeostasis and impairs spermiogenesis. [PDF]
Ou X+8 more
europepmc +1 more source
Multiple mating is not driven by size and sperm management in black soldier fly (Hermetia illucens)
We investigated mating in black soldier fly (BSF), Hermetia illucens (Diptera: Stratiomyidae), an important source of animal feed. The number of spermatozoa stored in the spermathecae of females does not change after one, two and three matings of the male. BSF males and females mate multiple times under controlled conditions. The number of sperm in the
Frédéric Manas+4 more
wiley +1 more source
Programming for Meiotic Competence in Mouse Male Germ Cells is Established at the Perinatal Precursor Stage of Development. [PDF]
Yang QE, Yang M, Oatley MJ, Oatley JM.
europepmc +1 more source
A guide to heat shock factors as multifunctional transcriptional regulators
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka+3 more
wiley +1 more source
Building a case for 'functional identity fraud' in eRpL22 paralogue-specific ribosomes in <i>Drosophila</i> germline development. [PDF]
Ware VC.
europepmc +1 more source
Ceratonia siliqua Protects Testicular Tissue in Ischemia/Reperfusion Injury
ABSTRACT Objectives Testicular torsion is a urological emergency with a risk of resulting in loss of testicular function due to ischemia/reperfusion injury (I/R) injury caused by oxidative stress. Ceratonia siliqua is known to decrease oxidative stress in urological pathologies. We investigated the protective effects of C.
Şahika Yardim+6 more
wiley +1 more source
Molecular Mechanisms Involved in Sperm Development, Maturation, and Fertilization. [PDF]
Álvarez-Rodríguez M, Catalán J.
europepmc +1 more source
An Increase in Male Recombination Rate With Age in Dairy Cattle Is Heritable and Polygenic
ABSTRACT Meiotic recombination is an essential process for shuffling genetic diversity in sexually reproducing organisms, can vary within and between individuals in response to intrinsic and extrinsic factors, and can be heritable. Interestingly, recombination rate has been found to vary with age in some species, but to date, there have been no ...
Evelyn Jade+5 more
wiley +1 more source