The Guangsi Yulin Decoction Inhibits Oxidative Stress and Inflammation-Induced Spermatogenesis Dysfunction <i>via</i> the <i>PTEN</i>/<i>PI3K</i>/<i>AKT</i>/<i>FoxO1</i> Pathway. [PDF]
Lin X +9 more
europepmc +1 more source
SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu +16 more
wiley +1 more source
Immunization Against a Conserved Short 13-Amino Acid Receptor-Binding Epitope of FSHβ Reduces Spermatogenesis and Sperm Motility in Male Mice. [PDF]
Liu X +6 more
europepmc +1 more source
BOLL‐Containing Aggregates Mediate the Translational Regulation During Human Oogenesis
This work elucidates that BOLL‐containing aggregate‐mediated translational control is essential for human oogenesis. These aggregates recruit PABPC1 and FXR1 to activate the translation of U‐rich mRNAs encoding cell cycle proteins, thereby ensuring successful meiotic progression.
Ying Li +5 more
wiley +1 more source
Diagnostic yield of OCT3/4 reflex testing in testicular biopsy
GCNIS detection frequency was 48/3353 (1.4%) testicular biopsies from 42/1870 (2.2%) men who underwent testicular biopsy with or without testicular sperm extraction (TESE). OCT3/4 was particularly helpful for detecting interstitial seminoma, GCNIS coexisting with mature spermatogenesis, and focal GCNIS.
Roselyne Choiniere +2 more
wiley +1 more source
The roles and mechanisms of Leydig cells and myoid cells in regulating spermatogenesis
Rui Zhou +7 more
semanticscholar +1 more source
Advances in the diagnosis and treatment of oligoasthenozoospermia based on epigenetic regulation. [PDF]
Zhao HB +5 more
europepmc +1 more source
The detrimental effects of conventional farming on bird biodiversity are increasingly documented. Despite this, the specific impacts of both organic and conventional farming practices on bird coloration and sperm quality in natural settings remain unexplored. This study aimed to determine whether these farming practices differentially affect body mass,
Ségolène Humann‐Guilleminot +5 more
wiley +1 more source
Dysregulated methylation of the human BOLL promoter hinders germ cell development from spermatogonia to spermatids. [PDF]
Lin TY +8 more
europepmc +1 more source
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne +4 more
wiley +1 more source

