Results 151 to 160 of about 102,741 (261)

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis

open access: yesCell Proliferation, EarlyView.
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu   +16 more
wiley   +1 more source

BOLL‐Containing Aggregates Mediate the Translational Regulation During Human Oogenesis

open access: yesCell Proliferation, EarlyView.
This work elucidates that BOLL‐containing aggregate‐mediated translational control is essential for human oogenesis. These aggregates recruit PABPC1 and FXR1 to activate the translation of U‐rich mRNAs encoding cell cycle proteins, thereby ensuring successful meiotic progression.
Ying Li   +5 more
wiley   +1 more source

Diagnostic yield of OCT3/4 reflex testing in testicular biopsy

open access: yesHistopathology, EarlyView.
GCNIS detection frequency was 48/3353 (1.4%) testicular biopsies from 42/1870 (2.2%) men who underwent testicular biopsy with or without testicular sperm extraction (TESE). OCT3/4 was particularly helpful for detecting interstitial seminoma, GCNIS coexisting with mature spermatogenesis, and focal GCNIS.
Roselyne Choiniere   +2 more
wiley   +1 more source

The roles and mechanisms of Leydig cells and myoid cells in regulating spermatogenesis

open access: yesCellular and Molecular Life Sciences, 2019
Rui Zhou   +7 more
semanticscholar   +1 more source

Field‐based evidence of impaired sperm quality associated with conventional farming in two passerine birds

open access: yesIbis, EarlyView.
The detrimental effects of conventional farming on bird biodiversity are increasingly documented. Despite this, the specific impacts of both organic and conventional farming practices on bird coloration and sperm quality in natural settings remain unexplored. This study aimed to determine whether these farming practices differentially affect body mass,
Ségolène Humann‐Guilleminot   +5 more
wiley   +1 more source

Dysregulated methylation of the human BOLL promoter hinders germ cell development from spermatogonia to spermatids. [PDF]

open access: yesMol Biol Rep
Lin TY   +8 more
europepmc   +1 more source

Proteomic analysis of the zone of degeneration at the mitosis–meiosis transition stage in wild‐caught male catshark (Scyliorhinus canicula), correlated with an unusually high‐water temperature in the English Channel

open access: yesJournal of Fish Biology, EarlyView.
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne   +4 more
wiley   +1 more source

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