Results 161 to 170 of about 168,606 (377)

Spermatogenesis following male germ-cell transplantation.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1994
In the adult male, a population of diploid stem-cell spermatogonia continuously undergoes self-renewal and produces progeny cells, which initiate the complex process of cellular differentiation that results in mature spermatozoa. We report here that stem
R. Brinster, James W. Zimmermann
semanticscholar   +1 more source

EP300‐interacting inhibitor of differentiation 3 is required for spermatogenesis in mice

open access: yesAndrology, EarlyView.
Abstract Background Mammalian spermatogenesis is a highly complex process of cell proliferation, meiosis, and differentiation. A series of genes are expressed in an orderly and precise manner to ensure spermatogenesis, with chromatin undergoing intricate changes throughout.
Ping Zhang   +7 more
wiley   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

open access: yesAndrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas   +6 more
wiley   +1 more source

Semen cryopreservation and storage in liquid nitrogen: Impact on chromatin compaction

open access: yesAndrology, EarlyView.
Abstract Background Sperm cryopreservation is a consolidate option for long‐term male fertility preservation. The freezing/thawing procedure causes detrimental effects to spermatozoa, including damage to viability, motility, membrane composition, and DNA, whereas the effect on sperm chromatin compaction is less studied.
Lara Tamburrino   +8 more
wiley   +1 more source

The Pulsatile Gonadorelin Pump Induces Earlier Spermatogenesis Than Cyclical Gonadotropin Therapy in Congenital Hypogonadotropic Hypogonadism Men

open access: yesAmerican Journal of Men's Health, 2019
The objective of this study was to compare the effect of pulsatile gonadorelin pump (PGP) and cyclical gonadotropin (human chorionic gonadotropin [HCG]/human menopausal gonadotropin [HMG]) therapy (CGT) on spermatogenesis in congenital hypogonadotropic ...
Luyao Zhang   +6 more
doaj   +1 more source

The Effect of Hydroalcoholic Extract of <i>Salvia miltiorrhiza</i> on Hormonal and Cellular Parameters of Spermatogenesis in Male Rats After the Consumption of Ibuprofen. [PDF]

open access: yesFood Sci Nutr
SM extract could be able to counter inflammation owing to the extra consumption of popular drugs such as ibuprofen. ABSTRACT Salvia miltiorrhiza (SM), a medicinal herb known for its antioxidant and anti‐inflammatory properties, has been traditionally used to treat various physiological disorders.
Salehi F   +3 more
europepmc   +2 more sources

Effects of X-ray irradiation on human spermatogenesis [PDF]

open access: yes, 1972
Direct cell kill and inhibition of mitosis have been suggested as mechanisms to explain the occurrence of absolute sterility following the irradiation of the testes.
Paulsen, C. A., Thorslund, T. W.
core   +1 more source

Inhibition of ROS1 activity with lorlatinib reversibly suppresses fertility in male mice

open access: yesAndrology, EarlyView.
Abstract Background Inhibition of sperm maturation in the epididymis is a promising post‐testicular strategy for short‐acting male contraceptives. It has been shown that ROS1, a receptor tyrosine kinase expressed in the epididymis, is essential for epididymal differentiation, sperm maturation, and male fertility in mice.
Yuki Oyama   +9 more
wiley   +1 more source

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