Homo sapiens, industrialisation and the environmental mismatch hypothesis
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley +1 more source
Laser Capture Microdissection: A New Tool for the Study of Spermatogenesis [PDF]
Carlos A. Suárez‐Quian +2 more
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Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao +7 more
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In Vitro Maintenance of Spermatogenesis in Xenopus Laevis Testis Explants Cultured in Serum-Free Media1 [PDF]
Michael S. Risley +2 more
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Spermatogonial stem cells and spermatogenesis in mice, monkeys and men
A. Fayomi, K. Orwig
semanticscholar +1 more source
SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu +16 more
wiley +1 more source
The Impact of <i>MEI1</i> Alternative Splicing Events on Spermatogenesis in Mongolian Horses. [PDF]
Song D +5 more
europepmc +1 more source
Quantitative (Stereological) Study of Normal Spermatogenesis in the Adult Monkey (Macaca fascicularis) [PDF]
Yang Zheng-wei +3 more
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Pubertal induction in prepubertal males with hypogonadotropic hypogonadism: testosterone or gonadotropins? [PDF]
Cavarzere P +4 more
europepmc +1 more source
The REGγ-Proteasome Regulates Spermatogenesis Partially by P53-PLZF Signaling [PDF]
Xiao Gao +15 more
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