Cadherin-18 loss in prospermatogonia and spermatogonial stem cells enhances cell adhesion through a compensatory mechanism. [PDF]
Li XX +13 more
europepmc +1 more source
MicroRNA Analysis of In Vitro Differentiation of Spermatogonial Stem Cells Using a 3D Human Testis Organoid System. [PDF]
Cohen AB +6 more
europepmc +1 more source
miR-1458 is inhibited by low concentrations of Vitamin B6 and targets TBX6 to promote the formation of spermatogonial stem cells in Rugao Yellow Chicken. [PDF]
Geng Q +7 more
europepmc +1 more source
Essential Regulation of YAP1 in Fate Determinations of Spermatogonial Stem Cells and Male Fertility by Interacting with RAD21 and Targeting NEDD4 in Humans and Mice. [PDF]
Li C +6 more
europepmc +1 more source
Human spermatogonial stem cells retain states with a foetal-like signature
Bush SJ +6 more
europepmc +1 more source
Spermatogonial stem cell regulation and spermatogenesis [PDF]
This article will provide an updated review of spermatogonial stem cells and their role in maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial stem cells (SSCs) will be described, along with research using these tools to enhance our understanding of stem cell biology and spermatogenesis.
Kyle Orwig +2 more
exaly +3 more sources
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Spermatogonial stem cell transplantation
Molecular and Cellular Endocrinology, 2000The development of the spermatogonial transplantation technique has given new impetus to research on spermatogonial stem cells. Possibilities opened by this technique include: (a) New ways to study fundamental aspects of spermatogenesis; (b) Generation of transgenic large domestic animals; (c) Protection of (young) male cancer patients from infertility
Izadyar, F. +4 more
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The biological activities of spermatogonial stem cells (SSCs) are the foundation for spermatogenesis and thus sustained male fertility. Therefore, understanding the mechanisms governing their ability to both self-renew and differentiate is essential.
Jon M, Oatley, Ralph L, Brinster
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Spermatogonial stem cells and spermatogenesis in mice, monkeys and men [PDF]
Continuous spermatogenesis in post-pubertal mammals is dependent on spermatogonial stem cells (SSCs), which balance self-renewing divisions that maintain stem cell pool with differentiating divisions that sustain continuous sperm production.
Fayomi Adetunji, Kyle Orwig
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Spermatogonial Stem Cell Development
2002Spermatogonial stem cells originate from primordial germ cells (PGCs) that derive from epiblast cells (embryonal ectoderm) (Lawson and Pederson 1992). During fetal development the PGCs proliferate and migrate to the genital ridges, where they become enclosed in the seminiferous cords formed by Sertoli cell precursors.
de Rooij, D.G. +3 more
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