Results 261 to 270 of about 359,437 (296)

The endoplasmic reticulum stress-ferroptosis reciprocal signaling orchestrates anti-tumor effect of anlotinib in anaplastic thyroid cancer

Cancer Cell International
Ferroptosis-induced therapy is a promising approach for treating anaplastic thyroid carcinoma (ATC), a highly lethal form of cancer. However, the specific effects of two anti-angiogenic agents, lenvatinib and anlotinib, on ferroptosis in ATC are not well
Yehao Guo, Juyong Liang, Lingling Ding, Jiajun Wu, Weidong Teng, Jiafeng Wang, Liehao Jiang, Zhuo Tan   +7 more
semanticscholar   +1 more source

Ivosidenib enhances cisplatin sensitivity in ovarian cancer by reducing cancer cell stemness

Cancer Drug Resistance
Aim: Cancer stem cells (CSCs) are pivotal in mediating platinum resistance in ovarian cancer. This study aimed to screen compounds sensitizing CSCs to cisplatin by using a small molecule inhibitor library.
Mengqing Chen, Lin Huang, Simei Zhao, Mengna Zhu, Si Sun, Wenhan Li, Jing Cai, Minggang Peng, Yiping Wen, Zehua Wang   +9 more
semanticscholar   +1 more source

Curcumin Enhances the Anti-Cancer Efficacy of CDK4/6 Inhibitors in Prostate Cancer.

Archivos españoles de urología
OBJECTIVE This study aimed to investigate the potential of combining cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors with curcumin (Cur), a natural compound known for its anti-aging properties, to enhance the anti-cancer efficacy in prostate cancer ...
Huandong Zhao, Ruimin Ding, Jiarui Han
semanticscholar   +1 more source

FOXN3 Downregulation in Colorectal Cancer Enhances Tumor Cell Stemness by Promoting EP300‐Mediated Epigenetic Upregulation of SOX12

Molecular Carcinogenesis
Cancer stemness plays a crucial role in promoting the progression of colorectal cancer (CRC). Forkhead box N3 (FOXN3) is a tumor suppressor protein. Herein, we investigated the role of FOXN3 in the regulation of CRC cell stemness.
Yanjie Xu, Ke Xie, Ling Li, Zhong Li, Qicheng Lu, Jin Feng   +5 more
semanticscholar   +1 more source

Aldehyde Dehydrogenese-1 High Cancer Stem-like Cells/Cancer-initiating Cells Escape from Cytotoxic T Lymphocytes due to Lower Expression of Human Leukocyte Antigen Class 1

Anticancer Research
Background/Aim: Human gastric cancer stem-like cells (CSCs)/cancer-initiating cells can be identified as aldehyde dehydrogenase-high (ALDHhigh) cells. Cancer immunotherapy employing immune checkpoint blockade has been approved for advanced gastric cancer
Tomohide Shirosaki, Noriko Kawai, Y. Ebihara, Aiko Murai, T. Kubo, R. Morita, Kenji Murata, T. Kanaseki, T. Tsukahara, T. Shichinohe, Y. Hirohashi, Satoshi Hirano, T. Torigoe   +12 more
semanticscholar   +1 more source

MiR-301b-3p targets and regulates EBF3 to impact the stem-like phenotype of breast cancer cells through glycolysis

Journal of clinical biochemistry and nutrition
Background: Cancer stem cells are essential for the development of tumors, their recurrence, metastasis, and resistance to treatment. Previous studies have shown that the silencing of EBF3 promotes the progression of malignant tumors, but its impact on ...
Jiankang Huang, Weidong Zhen, Xiaokai Ma, Suxia Ge, Ling Ma   +4 more
semanticscholar   +1 more source

Limitations and prospects of sphere-forming assay in culture of glioma stem cells

, 2012
Yifan Deng, Guang Yang, Shiguang Zhao
semanticscholar   +1 more source

The CRISPR–Cas toolbox for analytical and diagnostic assay development

Chemical Society Reviews, 2021
Wei Feng, Qianfan Yang, Feng Li
exaly  

Effects and Mechanisms of Anti-CD44 Monoclonal Antibody A3D8 on Proliferation and Apoptosis of Sphere-Forming Cells With Stemness From Human Ovarian Cancer

International Journal of Gynecologic Cancer, 2013
Yongrui Du, Ying Chen, Yan Gao, Xiulong Niu, Ya-jing Li, Weimin Deng   +5 more
semanticscholar   +1 more source

PD-L1 as a biomarker of response to immune-checkpoint inhibitors

Nature Reviews Clinical Oncology, 2021
Mary Beth Beasley, Lynette M Sholl, Sacha Gnjatic   +2 more
exaly