Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis. [PDF]
Kalvala AK +15 more
europepmc +1 more source
The imperatives of financial policy in the sphere of the digital economy: impacts on increasing investment activity and tax potential of Russian regions [PDF]
Agnessa O. Inshakova +2 more
openalex +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Distinct Roles of Matrigel Enabled the Production of Expandable Hepatoblast and Polarized Hepatocyte Organoids from Human Embryonic Stem Cells under 3-Dimensional Suspension Conditions. [PDF]
Wu H +9 more
europepmc +1 more source
The Eigensolutions of the Balance Equations Over a Sphere.
Antônio Divino Moura
openalex +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
PPARγ, a key modulator of metabolic reprogramming, stemness and chemoresistance associated with retrodifferentiation in human hepatocellular carcinomas. [PDF]
Daniel Y +19 more
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Impact of <sup>18</sup>F-FDG radioactivity outside the field of view on image quality in a SiPM-based time-of-flight dedicated breast PET scanner: a phantom study. [PDF]
Shiiba T +6 more
europepmc +1 more source
Aspects of Complexity in Quantum Evolutions on the Bloch Sphere [PDF]
Carlo Cafaro +2 more
openalex +1 more source

