Results 221 to 230 of about 316,592 (249)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The Fading Art of Microsphere-Derived Measurement of Absolute Myocardial Blood Flow. [PDF]

Ann Nucl Cardiol
Christian TF.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

First positronium lifetime imaging with scandium-44 on a long axial field-of-view PET/CT. [PDF]

Front Nucl Med
Mercolli L, Steinberger WM, Grundler PV, Moiseeva A, Braccini S, Conti M, Moskal P, Rathod N, Rominger A, Sari H, Schibli R, Seifert R, Shi K, Stepień EŁ, van der Meulen NP.   +14 more
europepmc   +1 more source

Study of the development of the value-semantic sphere of the personality of police officers of the Mongolian People's Republic

Anhtuul Bayartsajhan, Tatyana Maltseva, Oksana Milkevich   +2 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Evaluating the Ethos automated planning system for spatially fractionated radiotherapy. [PDF]

J Appl Clin Med Phys
Sait AA, Sa Y, Khemissi A, Patel U, Mani S, Paloor S, Hammoud R.   +6 more
europepmc   +1 more source

THE RESULTS OF PHENOLOGICAL OBSERVATIONS OF THE DEVELOPMENT OF THE GENERATIVE SPHERE OF PSEUDOTSUGA MENZIESII (MIRB.) FRANCO. IN THE VORONEZH REGION

A. A. Odintsov, Svetlana Degtyareva, Валентина Дорофеева   +2 more
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source