Results 91 to 100 of about 262,918 (303)

A 3D radiative transfer framework: IV. spherical & cylindrical coordinate systems

open access: yes, 2009
We extend our framework for 3D radiative transfer calculations with a non-local operator splitting methods along (full) characteristics to spherical and cylindrical coordinate systems.
Baron   +5 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Design Method for N-Lobed Noncircular Bevel Gears

open access: yesAdvances in Mechanical Engineering, 2020
As a type of spatial transmission mechanism, noncircular bevel gears (NBGs) can transfer power and motion between two intersecting axes with variable transmission following a suitable program of motion.
Kan Shi, Yan-An Yao, Shuai Lin
doaj   +1 more source

Painlev\'e-Gullstrand synchronizations in spherical symmetry

open access: yes, 2010
A Painlev\'e-Gullstrand synchronization is a slicing of the space-time by a family of flat spacelike 3-surfaces. For spherically symmetric space-times, we show that a Painlev\'e-Gullstrand synchronization only exists in the region where $(dr)^2 \leq 1$, $
Alicia Herrero   +30 more
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

A new method to compute quasi-local spin and other invariants on marginally trapped surfaces

open access: yes, 2009
We accurately compute the scalar 2-curvature, the Weyl scalars, associated quasi-local spin, mass and higher multipole moments on marginally trapped surfaces in numerical 3+1 simulations.
Jasiulek, Michael
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

CaMEL and ADCIRC Storm Surge Models—A Comparative Study

open access: yesJournal of Marine Science and Engineering, 2017
The Computation and Modeling Engineering Laboratory (CaMEL), an implicit solver-based storm surge model, has been extended for use on high performance computing platforms.
Muhammad K. Akbar   +3 more
doaj   +1 more source

Ionospheric Elementary Current Systems in Spherical Coordinates and Their Application.

open access: yesJournal of geomagnetism and geoelectricity, 1997
Two sets of basis functions in spherical coordinates are presented, in terms of which any given ionospheric current system, consisting of horizontal sheet currents and their accompanying field-aligned currents, can be expanded, regardless of any considerations on the ionospheric conductances or the electric field.
openaire   +2 more sources

Nonlocal dynamical potentials near curved surfaces [PDF]

open access: yes, 1998
We present a self-consistent quantum-mechanical formulation of the nonlocal dynamical potential near the surface of a solid describable in a coordinate system in which Laplace equation is separable.
Marušić, Leonardo, Šunjić, Marijan
core   +2 more sources

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