Comparative efficacy of Pirfenidone and Meloxicam on early radiotherapy-induced anal sphincter dysfunction in rats [PDF]
Frontiers in PharmacologyBackgroundRadiation therapy, integral to pelvic tumor management, impacts over half of all cancer patients and may lead to anal sphincter dysfunction due to inflammatory responses and chronic fibrotic remodeling in irradiated tissues.
Dragoș Viorel Scripcariu +13 more
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Hypertensive Pancreatic Sphincter [PDF]
Canadian Journal of Gastroenterology, 1998 Major papilla pancreatic sphincter dysfunction, a variant of sphincter of Oddi dysfunction, causes pancreatitis or pancreatic-type pain. Endoscopic manometry as performed at endoscopic retrograde cholangiography is the most commonly used method to ...
Glen A Lehman, Stuart Sherman
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Göttingen minipigs present with significant regeneration kinetics after sphincter injury compared to German landrace gilts; a feasibility study [PDF]
BMC Veterinary ResearchBackground Animals serve as important models for exploring the pathology, diagnosis, and therapy of different diseases and injuries. While smaller animals are preferred for bulk cohort studies, larger animals offer opportunities to investigate surgical ...
Jasmin Knoll +4 more
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Functional Assessment of Anal Sphincter with Transperineal Ultrasound and Its Relationship to Anal Continence [PDF]
DiagnosticsBackground/Objectives: Anal incontinence is linked to pelvic floor dysfunction. Diagnosis involves assessing both the function and structure of the anorectal unit.
Yaman Degirmenci +6 more
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A canine model of reversible urethral sphincter insufficiency [PDF]
Animal Models and Experimental MedicineThis study developed an animal model with internal and external urethral sphincter insufficiency by bypassing the sphincter without major damage so that the animal under study can return to normal life after the study.
Pourya Shokri +5 more
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Endofistula laser ablation of fistula-in-ano: a new minimally invasive technique for the treatment of fistula-in-ano [PDF]
Annals of Coloproctology, 2022 Purpose Many techniques are used to treat fistula-in-ano (FIA). The major problems associated with conventional surgical techniques are postoperative complications like sepsis, incontinence, etc.
Samuel Lalhruaizela
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Obstetrics and gynecology residents’ satisfaction and self-confidence after an anal sphincter injury simulation-based workshop in Indonesia: a pre- and post-intervention comparison study [PDF]
Journal of Educational Evaluation for Health Professions, 2022 Purpose Obstetric anal sphincter injury is one of the most common complications during delivery. Simulation models with manikins can be used as an effective medical learning method to improve students’ abilities before encountering patients.
Riska Wahyuningtyas +6 more
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A mechanics-based perspective on the pressure-cross-sectional area loop within the esophageal body
Frontiers in Physiology, 2023 Introduction: Plotting the pressure-cross-sectional area (P-CSA) hysteresis loops within the esophagus during a contraction cycle can provide mechanistic insights into esophageal motor function.
Guy Elisha +6 more
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Current status of stem cell treatments and innovative approaches for stress urinary incontinence
Frontiers in Medicine, 2022 Stem cells are capable of self-renewal, differentiation, and the promotion of the release of chemokines and progenitor cells essential for tissue regeneration. Stem cells have the potential to develop into specialized cells if given the right conditions,
Mehmet Murat Seval, Kazibe Koyuncu
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Frontiers in Surgery, 2022 BackgroundThere are many surgical methods of sphincter preservation in treating complex anal fistula, but the therapeutic effects of each operation are different.
Hua Huang +4 more
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