Results 21 to 30 of about 35,975 (233)
This study reveals the potential to manipulate spin‐valley polarization dynamics in MoSe2/WSe2 heterostructures by quantifying different scattering processes following selective photoexcitation. The results show that these heterostructures enable ultrafast valley‐selective charge transfer, with phonon scattering playing a significant role in the ...
Julian Wagner+9 more
wiley +1 more source
Tau protein plays a critical role in the pathology of Alzheimer's disease, utilizing extracellular vesicles (EVs) as a mechanism for intercellular transmission. This study develops a highly sensitive sandwich assay biosensor for detecting and quantifying tau‐associated EVs using surface‐enhanced Raman spectroscopy (SERS).
Saqer Al Abdullah+6 more
wiley +1 more source
Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han+9 more
wiley +1 more source
Loss of NR2F6 Protects from Salmonella Typhimurium Infection
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk+8 more
wiley +1 more source
Rational Design of Inner Ear Drug Delivery Systems
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu+5 more
wiley +1 more source
Nanopriming enhances plant resilience to environmental challenges; however, its effectiveness across diverse genetic backgrounds, including genetic modifications and natural variations, remains uncertain. These findings demonstrate that nanopriming improves efficacy when natural genetic variations are considered, particularly in genetically modified ...
Yining Wu+4 more
wiley +1 more source
Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang+6 more
wiley +1 more source
Quality‐enabled decentralized dynamic IoT platform with scalable resources integration
Abstract The Internet of Things (IoT) are standard inter connected devices aimed at join everyday object to the internet. This ecosystem include manufacturing, agriculture, smart cities, industry, as well as healthcare. The capacity of controlling and monitoring the objects of the physical world using IoT generate numerous opportunities.
Biswaranjan Bhola+7 more
wiley +1 more source
Microstructural Origin of Nonmonotonic Piezoresistivity in Polymer Nanocomposites
When polymer nanocomposites are subjected to tensile loading, the electrical resistance‐strain relationship may be nonmonotonic, hampering the use of these materials in real‐world applications. This challenge is addressed through the collaborative use of physical experimentation and computer simulations, establishing the inter‐nanotube junction ...
Ting Yui Wong+3 more
wiley +1 more source
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song+17 more
wiley +1 more source