Results 61 to 70 of about 46,898 (329)

Intrinsic stability of temporally shifted spike-timing dependent plasticity. [PDF]

open access: yesPLoS Computational Biology, 2010
Spike-timing dependent plasticity (STDP), a widespread synaptic modification mechanism, is sensitive to correlations between presynaptic spike trains and it generates competition among synapses.
Baktash Babadi, L F Abbott
doaj   +1 more source

Hippocampal Spike-Timing Correlations Lead to Hexagonal Grid Fields

open access: yes, 2017
Space is represented in the mammalian brain by the activity of hippocampal place cells as well as in their spike-timing correlations. Here we propose a theory how this temporal code is transformed to spatial firing rate patterns via spike-timing ...
Leibold, Christian   +1 more
core   +1 more source

GABAergic Circuits Control Spike-Timing-Dependent Plasticity [PDF]

open access: yesThe Journal of Neuroscience, 2013
The spike-timing-dependent plasticity (STDP), a synaptic learning rule for encoding learning and memory, relies on relative timing of neuronal activity on either side of the synapse. GABAergic signaling has been shown to control neuronal excitability and consequently the spike timing, but whether GABAergic circuits rule the STDP remained unknown.
Paille, V.   +6 more
openaire   +3 more sources

Spike timing dependent plasticity in the intact brain: counteracting spurious spike coincidences.

open access: yesFrontiers in Synaptic Neuroscience, 2010
A computationally rich algorithm of synaptic plasticity has been proposed based on the experimental observation that the sign and amplitude of the change in synaptic weight is dictated by the temporal order and temporal contiguity between pre- and post ...
Daniel E Shulz, Vincent Jacob
doaj   +1 more source

Forward Table-Based Presynaptic Event-Triggered Spike-Timing-Dependent Plasticity

open access: yes, 2016
Spike-timing-dependent plasticity (STDP) incurs both causal and acausal synaptic weight updates, for negative and positive time differences between pre-synaptic and post-synaptic spike events.
Augustine, Charles   +8 more
core   +1 more source

Neuromorphic, Digital and Quantum Computation with Memory Circuit Elements [PDF]

open access: yes, 2011
Memory effects are ubiquitous in nature and the class of memory circuit elements - which includes memristors, memcapacitors and meminductors - shows great potential to understand and simulate the associated fundamental physical processes.
Di Ventra, Massimiliano   +1 more
core   +1 more source

Synaptic plasticity in medial vestibular nucleus neurons: comparison with computational requirements of VOR adaptation [PDF]

open access: yes, 2010
Background: Vestibulo-ocular reflex (VOR) gain adaptation, a longstanding experimental model of cerebellar learning, utilizes sites of plasticity in both cerebellar cortex and brainstem.
Fabien Tell   +4 more
core   +6 more sources

Endocannabinoids mediate bidirectional striatal spike‐timing‐dependent plasticity [PDF]

open access: yesThe Journal of Physiology, 2015
Key points Although learning can arise from few or even a single trial, synaptic plasticity is commonly assessed under prolonged activation. Here, we explored the existence of rapid responsiveness of synaptic plasticity at corticostriatal synapses in a major synaptic learning rule, spike‐timing‐dependent plasticity (STDP).
Cui, Yihui   +7 more
openaire   +3 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Dynamic Control of Synaptic Plasticity by Competing Ferroelectric and Trap‐Assisted Switching in IGZO Transistors with Al2O3/HfO2 Dielectrics

open access: yesAdvanced Functional Materials, EarlyView.
A frequency‐tunable ferroelectric synaptic transistor based on a buried‐gate InGaZnO channel and Al2O3/HfO2 dielectric stack exhibits linear and reversible weight updates using single‐polarity pulses. By switching between ferroelectric and trap‐assisted modes depending on input frequency, the device simplifies neuromorphic circuit design and achieves ...
Ojun Kwon   +8 more
wiley   +1 more source

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