Results 51 to 60 of about 28,095 (262)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Advancing Neural Networks: Innovations and Impacts on Energy Consumption

Advanced Electronic Materials
The energy efficiency of Artificial Intelligence (AI) systems is a crucial and actual issue that may have an important impact on an ecological, economic and technological level.
Alina Fedorova, Nikola Jovišić, Jordi Vallverdù, Silvia Battistoni, Miloš Jovičić, Milovan Medojević, Alexander Toschev, Evgeniia Alshanskaia, Max Talanov, Victor Erokhin   +9 more
doaj   +1 more source

Evolving spiking neural network—a survey [PDF]

Evolving Systems, 2013
This paper provides a comprehensive literature survey on the evolving Spiking Neural Network (eSNN) architecture since its introduction in 2006 as a further extension of the ECoS paradigm introduced by Kasabov in 1998. We summarize the functioning of the method, discuss several of its extensions and present a number of applications in which the eSNN ...
Stefan Schliebs, Nikola K. Kasabov
openaire   +3 more sources

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Effects of Neural Assembles in Causal Inference Based on an Entropy-Maximization Bayesian Neural Network

IEEE Access
Causal inference is an important function of the nervous system. To explore causal inference, Bayesian inference performs as the possible framework, mapping neural implementation onto various cortical areas.
Weisi Liu, Xiaogang Pan
doaj   +1 more source

An artificial spiking afferent nerve based on Mott memristors for neurorobotics

Nature Communications, 2020
Though artificial sensory systems based on electronic devices have been realized, further transformation of data into spikes is required for neural network optimization. Here, based on NbO x Mott memristors, the authors report artificial spiking afferent
Xumeng Zhang, Ye Zhuo, Qing Luo, Zuheng Wu, Rivu Midya, Zhongrui Wang, Wenhao Song, Rui Wang, Navnidhi K. Upadhyay, Yilin Fang, Fatemeh Kiani, Mingyi Rao, Yang Yang, Qiangfei Xia, Qi Liu, Ming Liu, J. Joshua Yang   +16 more
doaj   +1 more source

Modeling Spiking Neural Networks on SpiNNaker [PDF]

Computing in Science & Engineering, 2010
SpiNNaker is a massively parallel architecture with more than a million processing cores that can model up to 1 billion spiking neurons in biological real time. © 2006 IEEE.
Jin, Xin, Luján, Mikel, Plana, Luis A., Davies, Sergio, Temple, Steve, Furber, Steve B.   +5 more
openaire   +1 more source

Claustrum Involvement in New Onset Refractory Status Epilepticus: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The claustrum sign is a distinctive neuroimaging finding characterized by bilateral T2/FLAIR hyperintensity of the claustrum, one of the most interconnected regions of the human brain. It was first described in new‐onset refractory status epilepticus (NORSE) and febrile infection–related epilepsy syndrome (FIRES).
Margherita Burani, Lorenzo Muccioli, Giada Giovannini, Niccolò Orlandi, Francesca Bisulli, Stefano Meletti   +5 more
wiley   +1 more source

A Practical Noise2Noise Denoising Pipeline for High‐Throughput Raman Spectroscopy

Advanced Engineering Materials, EarlyView.
A lightweight and reproducible denoising pipeline for high‐throughput Raman spectroscopy is introduced, based on a 1D convolutional autoencoder trained with a Noise2Noise strategy. Using only repeated short‐exposure acquisitions, the method suppresses stochastic noise without reference spectra, enabling reliable spectral reconstruction while preserving
David Martin‐Calle, Cesar Alvarez‐Llamas, Vincent Motto‐Ros, Christophe Dujardin, Jérémie Margueritat, David Rodney   +5 more
wiley   +1 more source

Optoelectronic Synaptic Devices Using Molecular Telluride Phase‐Change Inks for Three‐Factor Learning

Advanced Functional Materials, EarlyView.
Optoelectronic synaptic devices based on solution‐processed molecular telluride GST‐225 phase‐change inks are demonstrated for three‐factor learning. A global optical signal broadcast through a silicon waveguide induces non‐volatile conductance updates exclusively in locally electrically flagged memristors.
Kevin Portner, Dhananjeya Kumaar, Giacomo Torti, Killian Keller, Till Zellweger, Florian M. Schenk, Christoph Weilenmann, Daniel Chelladurai, Vara Prasad Jonnalagadda, Ghazi Sarwat Syed, Vanessa Wood, Jürg Leuthold, Alexandros Emboras, Maksym Yarema, Mathieu Luisier   +14 more
wiley   +1 more source