Results 51 to 60 of about 378,632 (352)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Quantum-to-classical crossover in the spin glass dynamics of cavity QED simulators

Physical Review Research
By solving the quench dynamics of a frustrated many-body spin-boson problem, we investigate the role of spin size on the dynamical formation of spin-glass order. In particular, we observe that quantum and classical spin glasses exhibit markedly different
Hossein Hosseinabadi, Darrick E. Chang, Jamir Marino   +2 more
doaj   +1 more source

Spin glass dynamics through the lens of the coherence length

Frontiers in Physics
Spin glass coherence lengths can be extracted from experiment and from numerical simulations. They encompasses the correlated region, and their growth in time makes them a useful tool for exploration of spin glass dynamics.
J. He, R. L. Orbach
doaj   +1 more source

Exploring the Different Degrees of Magnetic Disorder in Tb_xR_1−xCu₂ Nanoparticle Alloys

Nanomaterials, 2020
Recently, potential technological interest has been revealed for the production of magnetocaloric alloys using Rare-Earth intermetallics. In this work, three series of TbxR1−xCu2 (R ≡ Gd, La, Y) alloys have been produced in bulk and nanoparticle sizes ...
Elizabeth M. Jefremovas, María de la Fuente Rodríguez, Javier Alonso, Jesús Rodríguez Fernández, José Ignacio Espeso, Inés Puente-Orench, Daniel P. Rojas, Ana García-Prieto, María Luisa Fdez-Gubieda, Lidia Rodríguez Fernández, Luis Fernández Barquín   +10 more
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Overfrustrated and Underfrustrated Spin-Glasses in d=3 and 2: Evolution of Phase Diagrams and Chaos Including Spin-Glass Order in d=2

, 2013
In spin-glass systems, frustration can be adjusted continuously and considerably, without changing the antiferromagnetic bond probability p, by using locally correlated quenched randomness, as we demonstrate here on hypercubic lattices and hierarchical ...
Berker, A. Nihat, İlker, Efe, Ilker, Efe   +2 more
core   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Parallel Computing of Edwards—Anderson Model

Algorithms, 2021
A scheme for parallel computation of the two-dimensional Edwards—Anderson model based on the transfer matrix approach is proposed. Free boundary conditions are considered.
Mikhail Alexandrovich Padalko, Yuriy Andreevich Shevchenko, Vitalii Yurievich Kapitan, Konstantin Valentinovich Nefedev   +3 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Glass-forming property of hydroxyectoine is the cause of its superior function as a desiccation protectant

Frontiers in Microbiology, 2014
We were able to demonstrate that hydroxyectoine, in contrast to ectoine, is a good glass-forming compound. Fourier transform infrared (FTIR) and spin label electron spin resonance (ESR) studies of dry ectoine and hydroxyectoine have shown that the ...
Erwin Arno Galinski, Christoph eTanne, Andrea eMeffert, Elena A. Golovina, Folkert A. Hoekstra   +4 more
doaj   +1 more source