Results 81 to 90 of about 109,666 (262)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Spin-orbit Coupling Modulation in DNA by Mechanical Deformations

CHIMIA, 2018
We consider molecular straining as a probe to understand the mobility and spin active features of complex molecules. The strength of the spin-orbit interaction relevant to transport in a low dimensional structure depends critically on the ...
Solmar Varela Salazar, Vladimiro Mujica, Ernesto Medina   +2 more
doaj   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Time-resolved 3D imaging of ultrafast spin–orbit wave packet dynamics

New Journal of Physics, 2019
We combine bichromatic polarization pulse shaping with photoelectron imaging tomography for time-resolved spatial imaging of ultrafast spin–orbit wave packet (SOWP) dynamics in atoms.
Tim Bayer, Daniela Gräfing, Stefanie Kerbstadt, Dominik Pengel, Kevin Eickhoff, Lars Englert, Matthias Wollenhaupt   +6 more
doaj   +1 more source

Synthesis of a spin-labeled phospholipid for studying membrane dynamics in intact mammalian cells.

Journal of Lipid Research, 1988
We report here the synthesis of a spin-labeled phospholipid, 1-palmitoyl-2-(4-doxylpentanoyl)glycerophosphocholine. The synthetic route for this probe involves two major steps: 1) the synthesis of 4-doxylpentanoic acid from ethyl levulinate and 2-amino-2-
J Joseph, C S Lai
doaj   +1 more source

All-Optical Probe of Coherent Spin Waves

Physical Review Letters, 2002
A novel, all-optical method to excite and detect spin waves in magnetic materials is presented. By exploiting the temperature dependence of the magnetic anisotropy, an ultrashort laser pulse is efficiently converted in a picosecond "anisotropy field" pulse that triggers a coherent precession of the magnetization. Recording the temporal evolution of the
Kampen, van, M., Józsa, C., Kohlhepp, J.T., LeClair, P.R., Lagae, L., Jonge, de, W.J.M., Koopmans, B.   +6 more
openaire   +2 more sources

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Rotation-enhanced photonic spin Hall effect in a ring Bose–Einstein condensate

New Journal of Physics
We show that rotation can strongly amplify the photonic spin Hall effect in a ring Bose–Einstein condensate. For an incident probe beam carrying orbital angular momentum (OAM), the spin-dependent transverse shift of the reflected light is weak in the non-
Leibo Deng, Muqaddar Abbas, Ghaisud Din, Hocine Bahlouli, Yong-Hong Ma   +4 more
doaj   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier, Françoise Heran, Francis Lallemand, Pierre Bourdillon   +3 more
wiley   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source