Advanced Functional Materials, EarlyView.Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim +8 more
wiley +1 more source
Supervariate Gel Transforms into Various Biominerals in Salt Solutions
Advanced Functional Materials, EarlyView.It is revealed that common calcium‐based biominerals can form from a stable, non‐toxic ‘supervariate’ gel. This tunable gel selectively yields calcite or hydroxyapatite in carbonate/phosphate solutions, while CaCl₂ facilitates the formation of dihydrate calcium pyrophosphate, which converts to hydroxyapatite upon drying. These findings provide insights
Xinxue Tang +12 more
wiley +1 more source
Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders
Advanced Functional Materials, EarlyView.This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao +5 more
wiley +1 more source
STUDIES IN THE PHYSIOLOGY OF THE CENTRAL NERVOUS SYSTEM. III. THE GENERAL CONDITION OF THE SPINAL VASO‐MOTOR PATHS IN SPINAL SHOCK [PDF]
, 1913 F. H. Pike
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Advanced Functional Materials, EarlyView.A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee +12 more
wiley +1 more source
The cranial and first spinal nerves of menidia; A contribution upon the nerve components of the bony fishes. Section 1. Introductory [PDF]
, 1899 C. Judson Herrick
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Chemo‐Mechanical Coupling in Hydrogels: Dynamics in the Diffusion‐Limited Regime
Advanced Functional Materials, EarlyView.A time‐dependent continuum model is developed to capture the transient swelling dynamics of chemo‐mechanical hydrogels. By coupling chemical reactions, solvent transport, and polymer deformation, volume phase transitions, reaction kinetics, and transient mechanical instabilities are analyzed.
Yao Xiong +2 more
wiley +1 more source
Pyogenic infective Diseases of the Brain Spinal Cord; Meningitis; Abscess Brain; Infective Sinus Thrombosis. By Macewen William, M. D. Glasgow: James Maclehose and Sons. 1893. [PDF]
, 1894 D. Norman Grant
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Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury
Advanced Functional Materials, EarlyView.After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen +9 more
wiley +1 more source
A Case in Which Acute Spasmodic Pain in the Left Lower Extremity Was Completely Relieved by Sub-Dural Division of the Posterior Roots of Certain Spinal Nerves, All other Treatment Having Proved Useless. Death from Sudden Collapse and Cerebral Hæmorrhage on the Twelfth Dat after the Operation, at the Commencement of Apparent Convalescence [PDF]
, 1889 William H. Bennett
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