A Brain–Spinal Interface Alleviating Gait Deficits after Spinal Cord Injury in Primates
Nature, 2016 Spinal cord injury disrupts the communication between the brain and the spinal circuits that orchestrate movement. To bypass the lesion, brain–computer interfaces have directly linked cortical activity to electrical stimulation of muscles, and have thus ...
M. Capogrosso +20 more
semanticscholar +1 more source
Origins of Neural Progenitor Cell-Derived Axons Projecting Caudally after Spinal Cord Injury. [PDF]
, 2019 Neural progenitor cells (NPCs) transplanted into sites of spinal cord injury (SCI) extend large numbers of axons into the caudal host spinal cord. We determined the precise locations of neurons in the graft that extend axons into the caudal host spinal ...
Anil, Selin +7 more
core
Current evidence for treatment with nusinersen for spinal muscular atrophy : a systematic review [PDF]
, 2019 Recent discovery of nusinersen, an antisense oligonucleotide drug, has provided encouragement for improving treatment of spinal muscular atrophy. No therapeutic options currently exist for this autosomal recessive motor neuron disorder.
Meylemans, Antoon, De Bleecker, Jan
core +1 more source
Spinal cystic echinococcosis - a systematic analysis and review of the literature : part 2. treatment, follow-up and outcome [PDF]
, 2013 Bone involvement in human cystic echinococcosis (CE) is rare, but affects the spine in approximately 50% of cases. Despite significant advances in diagnostic imaging techniques, surgical treatment and introduction of pharmacological therapy, spinal ...
Blum, Johannes +4 more
core +3 more sources
AMPA Receptor Phosphorylation and Synaptic Colocalization on Motor Neurons Drive Maladaptive Plasticity below Complete Spinal Cord Injury. [PDF]
, 2015 Clinical spinal cord injury (SCI) is accompanied by comorbid peripheral injury in 47% of patients. Human and animal modeling data have shown that painful peripheral injuries undermine long-term recovery of locomotion through unknown mechanisms ...
Beattie, Michael S +7 more
core +1 more source
Analysis of current density and related parameters in spinal cord stimulation [PDF]
, 1998 A volume conductor model of the spinal cord and surrounding anatomical structures is used to calculate current (and current density) charge per pulse, and maximum charge density per pulse at the contact surface of the electrode in the dorsal epidural ...
Boom, Herman B.K. +2 more
core +3 more sources
Pakistan Armed Forces Medical Journal, 2020 Objective: To determine the efficacy of intramuscular phenylephrine for maintenance of maternal hemodynamics in caesarean section under spinal anesthesia. Study Design: Case series.
Muhammad Saeed +5 more
doaj
\u3cem\u3eEx Vivo\u3c/em\u3e Diffusion Tensor Imaging of Spinal Cord Injury in Rats of Varying Degrees of Severity [PDF]
, 2013 The aim of this study was to characterize magnetic resonance diffusion tensor imaging (DTI) in proximal regions of the spinal cord following a thoracic spinal cord injury (SCI). Sprague–Dawley rats (n = 40) were administered a control, mild, moderate, or
Jirjis, Michael +2 more
core +1 more source
A validation of the Oswestry Spinal Risk Index [PDF]
, 2016 Purpose The purpose of this study was to validate the Oswestry Spinal Risk Index (OSRI) in an external population. The OSRI predicts survival in patients with metastatic spinal cord compression (MSCC).
A Leithner +21 more
core +1 more source
Advanced Biomedical Research, 2012 Background: The antiemetic efficacy of midazolam and ondansetron was shown before. The aim of the present study was to compare efficacy of using intravenous midazoalm, ondansetron, and midazolam in combination with ondansetron for treatment of nausea and
Mitra Jabalameli +3 more
doaj +1 more source