Results 221 to 230 of about 81,926 (354)

Regulation of Chondrocyte Metabolism and Osteoarthritis Development by Sirt5 Through Protein Lysine Malonylation

Arthritis &Rheumatology, EarlyView.
Objective Chondrocytemetabolic dysfunction plays an important role in osteoarthritis (OA) development during aging and obesity. Protein posttranslational modifications (PTMs) have recently emerged as an important regulator of cellular metabolism. We aim to study one type of PTM, lysine malonylation (MaK), and its regulator sirtuin 5 (Sirt5) in OA ...
Huanhuan Liu, Anupama Binoy, Siqi Ren, Thomas C. Martino, Anna E. Miller, Craig R. G. Willis, Shivakumar R. Veerabhadraiah, Joanna Bons, Jacob P. Rose, Birgit Schilling, Michael J. Jurynec, Shouan Zhu   +11 more
wiley   +1 more source

In Patients not Suitable for Generalised Anaesthesia, Surgery for Necrotising Fasciitis under Spinal Anaesthesia should be Considered. [PDF]

Malays Orthop J
Finsterer J, Zarrouk S.
europepmc   +1 more source

EFFECT OF INJECTED VOLUME AND SPEED OF INJECTION ON THE SPREAD OF SPINAL ANAESTHESIA WITH ISOBARIC AMETHOCAINE

, 1982
J. H. McClure, David T. Brown, J.A.W. WILDSMJTH   +2 more
openalex   +1 more source

"Rachi-resistance" and Spinal Anaesthesia [PDF]

BMJ, 1937
W. R. Black, G. A. Bagot Walters
openaire   +3 more sources

Expert Perspective: How, When, and Why to Potentially Stop Antiresorptive Drugs in Osteoporosis

Arthritis &Rheumatology, EarlyView.
Osteoporosis is a chronic disease, and antiresorptive treatments are often continued for many years. Despite their established efficacy in reducing fracture risk, the most commonly used antiresorptive treatments, bisphosphonates and denosumab, have short‐ and long‐term risks that, coupled with their benefits and other unique characteristics, influence ...
Giovanni Adami, Kenneth G. Saag
wiley   +1 more source

EFFECTS OF POSTURE AND BARICITY ON SPINAL ANAESTHESIA WITH 0.5% BUPIVACAINE 5 ML

, 1988
R.W.D. MITCHELL, G.M.R. BOWLER, D.B. Scott, H. H. Edström   +3 more
openalex   +1 more source

Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and Tyk2 Inhibitors via Interleukin‐10 Antagonism

Arthritis &Rheumatology, EarlyView.
Objective JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but Tyk2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn disease, which highlights the complex role for JAK/STAT signaling in different inflammatory processes.
Sami Giryes, Chi Wong, Charlie Bridgewood, Mark Harland, Ala Altaie, Nicole McDermott, Kerem Abacar, Abhay Rao, Almas Khan, Tristan McMillan, Peter Loughenbury, Robert Dunsmuir, Vishal Borse, Tom Macleod, Dennis McGonagle   +14 more
wiley   +1 more source

Hypotension after unilateral versus bilateral spinal anaesthesia: A Systematic review with meta-analysis. [PDF]

Eur J Anaesthesiol
Gong C, Ye X, Liao Y, Ye P, Zheng T, Zheng X.   +5 more
europepmc   +1 more source

Anaesthetic Management for Mastectomy in a Male With Unilateral Gynecomastia: The Utilization of Thoracic Segmental Spinal Anaesthesia and Erector Spinae Plane Block. [PDF]

Cureus, 2023
Paul A, Borkar A.
europepmc   +1 more source

SPINAL ANAESTHESIA IN OBSTETRICS

British Journal of Anaesthesia, 1991
openaire   +3 more sources