Results 181 to 190 of about 103,063 (318)

The Impact of Fentanyl and Morphine on Maternal Hemodynamics in Spinal Anesthesia for Cesarean Section. [PDF]

open access: yesPharmaceuticals (Basel)
Moisa RC   +5 more
europepmc   +1 more source

Controversies in spine research: Organ culture versus in vivo models for studies of the intervertebral disc

open access: yesJOR SPINE, Volume 5, Issue 4, December 2022., 2022
Abstract Intervertebral disc degeneration is a common cause of low back pain, the leading cause of disability worldwide. Appropriate preclinical models for intervertebral disc research are essential to achieving a better understanding of underlying pathophysiology and for the development, evaluation, and translation of more effective treatments.
Shirley N. Tang   +13 more
wiley   +1 more source

A Qualitative analysis of parturients' experience of spinal anesthesia and postoperative complaints. [PDF]

open access: yesSaudi J Anaesth
Arunachalam R   +6 more
europepmc   +1 more source

Palladium Nanoparticles Degrade Advanced Glycation End Products via Valosin‐Containing Protein Mediated Autophagy to Attenuate High‐Glucose/High‐Fat‐Induced Intervertebral Disc Degeneration

open access: yesExploration, EarlyView.
Illustration of Pd NP‐mediated rescue of HGHF (or advanced glycation end products [AGEs])‐induced IVD degeneration by targeting AGEs degradation. Pd NPs promote the ATPase activity of VCP and upregulate autophagosome formation to degrade AGEs. Consequently, Pd NPs alleviate the oxidative and ER stress, protect the structure and function of mitochondria,
Xiao Yang   +13 more
wiley   +1 more source

MiR‐33‐5p alleviates spinal cord injury in rats and protects PC12 cells from lipopolysaccharide‐induced apoptosis

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 39, Issue 1, Page 52-60, January 2023., 2023
Abstract MicroRNAs (miRNAs) exert critical effects in spinal cord injury (SCI). The miR‐33‐5p level is found to be lower in rats with SCI compared with that in control (untreated) and sham‐operated (laminectomy but no contusion) rats. Therefore, we investigated the biological functions of miR‐33‐5p and related mechanisms in SCI pathogenesis and ...
Zhe Li   +2 more
wiley   +1 more source

Retroperitoneal hemorrhage following spinal anesthesia: A case report. [PDF]

open access: yesSaudi J Anaesth
Hawsawi H   +3 more
europepmc   +1 more source

Drug delivery pathways to the central nervous system via the brain glymphatic system circumventing the blood‐brain barrier

open access: yesExploration, EarlyView.
The discovery of the glymphatic system has opened up a pathway for drug delivery to the brain by circumventing the blood‐brain barrier, which can effectively improve drug utilization. The methods of drug delivery through the glymphatic system include intrathecal injection, intranasal injection, and delivery through the meningeal lymphatic vessels.
Xiang Wang   +7 more
wiley   +1 more source

CircUCK2 regulates HECTD1‐mediated endothelial‐mesenchymal transition inhibition by interacting with FUS and protects the blood–brain barrier in ischemic stroke

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 39, Issue 1, Page 40-51, January 2023., 2023
Abstract Ischemic stroke (IS) has become a cerebrovascular disease of widespread concern. Overexpression of circUCK2 alleviates neuronal damage in IS. However, the specific regulatory mechanisms of circUCK2 are not fully understood. In this study, we found that circUCK2 and HECT domain E3 ubiquitin ligase 1 (HECTD1) were downregulated in IS models in ...
Jun‐Hong Zhuang   +8 more
wiley   +1 more source

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