Results 181 to 190 of about 1,047,807 (407)
ABDUCENS NERVE PALSY FOLLOWING SPINAL ANESTHESIA [PDF]
CAPTAIN BENJAMIN STEINBERG +1 more
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This study systematically explores the action mechanism of Pon3 and its regulatory targets in spinal cord injury (SCI). It demonstrates that Dnmt1 regulates Pon3 expression by modulating methylation levels, thereby inhibiting S1PR1‐mediated pyroptosis and improving SCI prognosis.
Birong Peng +8 more
wiley +1 more source
THE COMPARATIVE INCIDENCE OF POSTLUMBAR PUNCTURE HEADACHE FOLLOWING SPINAL ANESTHESIA ADMINISTERED THROUGH 20 AND 24 GAUGE NEEDLES [PDF]
L. M. HARRIS, M. H. HARMEL
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Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan +9 more
wiley +1 more source
Background and purpose: Postoperative pain is a common problem after hysterectomy. The purpose of this study was to compare the effect of general anesthesia and spinal anesthesia on pain intensity and hemodynamic changes after abdominal hysterectomy ...
Hakimeh Alereza +4 more
doaj
A MALLEABLE CONE-TIP NEEDLE FOR FRACTONAL SPINAL ANESTHESIA [PDF]
Bernard E. Cappe, Enoch V. Deutsch
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By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao +14 more
wiley +1 more source
Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi +18 more
wiley +1 more source

