Results 191 to 200 of about 1,047,807 (407)

Allele‐Specific Regulation of PAXIP1‐AS1 by SMC3/CEBPB at rs112651172 in Psychiatric Disorders Drives Synaptic and Behavioral Dysfunctions in Mice

open access: yesAdvanced Science, EarlyView.
This study identifies a functional noncoding variant, rs112651172 (C/G), that drives allele‐specific expression of PAXIP1‐AS1 in monozygotic twin pairs discordant for schizophrenia and bipolar disorder. The risk G allele enhances CEBPB binding, leading to lncRNA upregulation, CNTNAP3 derepression, and synaptic and behavioral deficits in mice.
Chaoying Ni   +14 more
wiley   +1 more source

A Comparison of Bispectral Index between Spinal and Epidural Anesthesia during Cesarean Section

open access: yesمجله دانشکده پزشکی اصفهان, 2012
Background: Many studies have shown spinal anesthesia with sedative drugs to affect bispectral index (BIS). On the other hand, spinal anesthesia, even without sedative drugs, reduces the level of consciousness.
Mitra Jabalameli, Nahid Baghban Nikoo
doaj  

Estrogen Alleviates Sevoflurane‐Induced Neurotoxicity by Inhibiting ERα‐Tau Binding

open access: yesAdvanced Science, EarlyView.
Sevoflurane‐induced neurotoxicity exhibits sex differences, and estrogen can mitigate these effects; however, its protective action appears to be time‐window dependent, which may be related to the competitive binding of estrogen and Tau to ERα. Abstract Sevoflurane‐induced neurotoxicity is age‐dependent, but the role of sex differences is unclear ...
Feixiang Li   +8 more
wiley   +1 more source

Pulmonary Emboli Manifestation during Spinal Anesthesia for Cesarean Section in two Pregnant Women

open access: yesNovelty in Biomedicine, 2015
Background: Pregnancy causes a small increase in risk of venous thromboembolism (VTE), but a large increase in concern upon presentation during cesarean section with symptoms of pulmonary embolism (PE).
Mastaneh Dahi, Seyed Amir Mohajerani
doaj  

Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells‐Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation

open access: yesAdvanced Science, EarlyView.
This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li   +9 more
wiley   +1 more source

Confidence of Medical Students Performing Endotracheal Intubation and Spinal Anesthesia and Accuracy of Their Practices.

open access: yesJournal of Health Science and Medical Research (JHSMR), 2013
Objective: Endotracheal intubation and spinal anesthesia are essential skills required for each medical student. This study was conducted to assess the confidence and accuracy of medical students in performing these two procedures as well as to evaluate ...
Sasikaan Nimmaanrat
doaj  

Advanced Image‐Guidance and Surgical‐Navigation Techniques for Real‐Time Visualized Surgery

open access: yesAdvanced Science, EarlyView.
This review comprehensively summarizes advances in surgical navigation, covering both established and emerging intraoperative imaging technologies. It highlights mechanisms, advantages, limitations, and clinical applications, while emphasizing interdisciplinary collaboration.
Xiaoxiao Fan   +9 more
wiley   +1 more source

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