Results 31 to 40 of about 104,119 (216)

Multimodal Soft Surgical Robots Enabled by Eco‐Degradable, Sterilizable Polymers and Transient Electronics

open access: yesAdvanced Functional Materials, EarlyView.
A compostable PGS soft surgical robot with interchangeable modules integrates transient Mo tactile and Si thermal sensors for dual feedback. The device preserves its function after clinical‐grade sterilization, demonstrates stable actuation and cardiac tissue grasping with real‐time in vivo pulsatile monitoring, and biodegrades post‐use with soil‐safe, 
Minseong Chae   +27 more
wiley   +1 more source

Comparing the efficacy and safety of unilateral versus bilateral spinal anesthesia: a meta-analysis and systematic review

open access: yesAnnals of Medicine
Background Unilateral spinal anesthesia has gained increasing attention in recent years. Emerging evidence suggests that it provides comparable analgesia to conventional bilateral spinal anesthesia while reducing adverse effects, and its efficacy and ...
Ji-Xiang Wan   +5 more
doaj   +1 more source

Spatiotemporal Drug Delivery via a Neonatal Spinal Cord ECM Hydrogel for Biomimetic Microenvironment Remodeling After Spinal Cord Injury

open access: yesAdvanced Functional Materials, EarlyView.
A biomimetic hydrogel derived from neonatal spinal cord ECM (DNSCM) delivers LAMB2 protein and ISP peptide to remodel the inhibitory injury microenvironment. The system sustains drug release, upregulates pro‐regenerative LAMB2, downregulates inhibitory CSPG, and promotes axonal regeneration.
Shiyu Fu   +8 more
wiley   +1 more source

Comparative analysis of spinal anesthesia versus general anesthesia in single-port access laparoscopic adnexal surgery: a propensity score matching study

open access: yesBMC Women's Health
This study evaluated the safety and efficacy of spinal anesthesia as an alternative to general anesthesia in single-port access (SPA) laparoscopic adnexal surgeries. 110 patients were recruited and, after propensity score matching, 63 (general anesthesia:
Kyung Jin Eoh   +7 more
doaj   +1 more source

Effect of General and Spinal Anesthesia on Hepatic and Renal functions and Hemodynamic parameters of Iraqi Women Undergo Cesarean Section: Comparative Study

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2018
Both general and spinal anesthesia can be use during caesarean section. Spinal anesthesia is preferred by anesthesiologists and gynecologists because of its beneficial effects for both mothers and their fetuses.
Ola K. Mohammed   +4 more
doaj   +1 more source

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

open access: yesAdvanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni   +5 more
wiley   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang   +13 more
wiley   +1 more source

Hyperalgesia and Reduced Offset Analgesia During Spinal Anesthesia

open access: yesJournal of Pain Research, 2020
Elske Sitsen, Monique van Velzen, Mischa de Rover, Albert Dahan, Marieke Niesters Department of Anesthesiology, Leiden University Medical Center, Leiden, RC 2300, the NetherlandsCorrespondence: Marieke NiestersDepartment of Anesthesiology, Leiden ...
Sitsen E   +4 more
doaj  

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

open access: yesAdvanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu   +16 more
wiley   +1 more source

The Relationship between the Phases of the Menstrual Cycle on the Incidence and Severity of Headache after Spinal Anesthesia

open access: yesThe Surgery Journal, 2019
Introduction Headache after spinal anesthesia is a common complication, which is caused after dural puncture due to discharge of cerebrospinal fluid and reduction in the volume and pressure.
Mahmoud reza Moradkhani   +3 more
doaj   +1 more source

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