Protocol to prepare mouse spinal cord for patch-clamp and histology experiments
Summary: The spinal cord is a part of the central nervous system located within the spinal canal of the vertebrae. Here, we present a protocol to prepare mouse spinal cord sections for patch-clamp and histology experiments.
Sang-Hyeon Ju, Jong-Woo Sohn
doaj +1 more source
Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation [PDF]
Background: Ascending/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL-IVDH) in dogs. Hypothesis/Objectives: To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with ...
Aikawa +34 more
core +1 more source
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias +4 more
wiley +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Foxj1a is expressed in ependymal precursors, controls central canal position and is activated in new ependymal cells during regeneration in zebrafish [PDF]
Zebrafish are able to regenerate the spinal cord and recover motor and sensory functions upon severe injury, through the activation of cells located at the ependymal canal.
Ana Ribeiro +4 more
doaj +1 more source
MRI-based Surgical Planning for Lumbar Spinal Stenosis
The most common reason for spinal surgery in elderly patients is lumbar spinal stenosis(LSS). For LSS, treatment decisions based on clinical and radiological information as well as personal experience of the surgeon shows large variance.
Andrew J. Haig +12 more
core +1 more source
This review critically reassesses our prior hypothesis and proposes a revised anatomical model of the fusion fascia that is broadly applicable to GI cancer surgeries grounded in the principles of mesenteric resection. Our synthesis suggests that the fusion fascia is neither a dense connective tissue membrane nor a remnant of mesothelial fusion, but ...
Hisashi Shinohara +9 more
wiley +1 more source
EVALUATION OF THE DEGREE OF STENOTIC PROCESS (STENOSIS) OF THE SPINAL CANAL AT THE LUMBAR LEVEL
In the article the evaluation of the degree of stenotic process in the spinal canal in 48 patients with stenosis of the spine judging by the morphometric measurements of vertebrae, dural sac and spinal canal.
V. A. Sorokovikov +3 more
doaj
Clinical features of ligamentosis in lumbar spinal stenosis in patients of different agе
Introduction. Ligamentosis of lumbar spinal canal are rare and not well investigated pathology.Materials and methods. From our patients with lumbar spinal stenosis we took that, which had changes in spinal ligamentsResults.
Yuriy Pedachenko, Elena Krasilenko
doaj +1 more source
Simultaneous submicrometric 3D imaging of the micro-vascular network and the neuronal system in a mouse spinal cord [PDF]
Defaults in vascular (VN) and neuronal networks of spinal cord are responsible for serious neurodegenerative pathologies. Because of inadequate investigation tools, the lacking knowledge of the complete fine structure of VN and neuronal systems is a ...
Battaglia, Giuseppe +13 more
core +3 more sources

