Results 31 to 40 of about 29,285 (251)

National trends in lumbar spine decompression and fusion surgery in Finland, 1997–2018

Acta Orthopaedica, 2021
Background and purpose — During recent years, spine surgery techniques have advanced, the population has become older, and multiple high-quality randomized controlled trials that support surgical treatment for degenerative spinal stenosis and ...
Ville T Ponkilainen, Tuomas T Huttunen, Marko H Neva, Liisa Pekkanen, Jussi P Repo, Ville M Mattila   +5 more
doaj   +1 more source

A real-world analysis of hybrid CDA and ACDF compared to multilevel ACDF

BMC Musculoskeletal Disorders, 2023
Background Multilevel anterior cervical discectomy and fusion (mACDF) is the gold standard for multilevel spinal disease; although safe and effective, mACDF can limit regular spinal motion and contribute to adjacent segment disease (ASD). Hybrid surgery,
Kee D Kim, Domagoj Coric, Armen Khachatryan, Brenna L Brady, Timothy Lillehaugen, Mike McCormack, William B Dolman, Richard Ditto   +7 more
doaj   +1 more source

Surgery rates for lumbar spinal stenosis in Denmark between 2002 and 2018: a registry-based study of 43,454 patients

Acta Orthopaedica, 2022
Background and purpose: Over the last decades, many countries have shown increased surgery rates for lumbar spinal stenosis (LSS), but little information is available from Denmark.
Rikke K Jensen, Berit Schiøttz-Christensen, Christian Volmar Skovsgaard, Mathias Thorvaldsen, Rune Mygind Mieritz, Andreas K Andresen, Henrik Wulff Christensen, Jan Hartvigsen   +7 more
doaj   +1 more source

Time trends in spine surgery in Italy: a nationwide, population-based study of 1,560,969 records of administrative health data from 2001 to 2019

Acta Orthopaedica
Background and purpose: The use of spinal implants has increased substantially. Their widespread use raises public health concerns. We aimed to study spinal surgery trends in Italy from 2001 to 2019 and present a mapping for ICD9-CM codes potentially ...
Marina Torre, Andrea Piazzolla, Enrico Ciminello, Tiziana Falcone, Eugenio Carrani, Simona Pascucci, Michela Franzò, Giuseppe Barbagallo, Vincenzo Vitiello, Gustavo Zanoli, Alessia Biondi, Letizia Sampaolo, Veronica Mari, Francesco Langella, Pedro Berjano   +14 more
doaj   +1 more source

Partial conservation between mice and humans in olfactory bulb interneuron transcription factor codes

Frontiers in Neuroscience, 2016
The mammalian main olfactory bulb (OB) has a large population of GABAergic inhibitory interneurons that contains several subtypes defined by the co-expression other neurotransmitters and calcium binding proteins.
Nana Fujiwara, John W Cave, John W Cave
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Impact of Cirrhosis on Morbidity and Mortality After Spinal Fusion

Global Spine Journal, 2020
Study Design: Retrospective large database study. Objective: To determine the impact of cirrhosis on perioperative outcomes and resource utilization in elective spinal fusion surgery.
Young Lu MD, Charles C. Lin BSE, Hayk Stepanyan MD, Andrew P. Alvarez MD, Nitin N. Bhatia MD, P. Douglas Kiester MD, Charles D. Rosen MD, Yu-Po Lee MD   +7 more
doaj   +1 more source

Reasons for delayed spinal cord decompression in individuals with traumatic spinal cord injuries in Iran: A qualitative study from the perspective of neurosurgeons

Chinese Journal of Traumatology, 2021
Purpose: The median time from the event leading to the spinal cord injury (SCI) to the time of decompressive surgery is estimated to be 6.9 days in Iran, which is much longer than the proposed ideal time (less than 24 h) in published guidelines.
Masoud SohrabiAsl, Zahra Ghodsi, Roya Habibi Arejan, Zahra Azadmanjir, Mahdi Sharif-Alhoseini, Moein Khormali, Maryam Shojaei, Abbas Rahimiforoushani, Alireza Khoshnevisan, Alexander R. Vaccaro, Michael G. Fehlings, Vafa Rahimi-Movaghar   +11 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Stability of the Subaxial Spine after Penetrating Trauma: Do Classification Systems Apply?

Advances in Orthopedics, 2018
Objective. Blunt spinal trauma classification systems are well established and provide reliable treatment algorithms. To date, stability of the spine after civilian gunshot wounds (CGSWS) is poorly understood.
Jackson Rucker Staggers, Thomas Elliot Niemeier, William E. Neway, Steven Michael Theiss   +3 more
doaj   +1 more source