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Activity-based recovery training with spinal cord epidural stimulation improves standing performance in cervical spinal cord injury [PDF]

Journal of NeuroEngineering and Rehabilitation
Background Individuals with a clinically complete spinal cord injury are unable to stand independently without external assistance. Studies have shown the combination of spinal cord epidural stimulation (scES) targeted for standing with activity-based ...
Claudia A. Angeli, Enrico Rejc, Beatrice Ugiliweneza, Maxwell Boakye, Gail F. Forrest, Katelyn Brockman, Justin Vogt, Brittany Logsdon, Katie Fields, Susan J. Harkema   +9 more
doaj   +2 more sources

Walking naturally after spinal cord injury using a brain–spine interface

Nature, 2023
A reliable digital bridge restored communication between the brain and spinal cord and enabled natural walking in a participant with spinal cord injury. A spinal cord injury interrupts the communication between the brain and the region of the spinal cord
H. Lorach, Andrea Gálvez, Valeria Spagnolo, Félix Martel, Serpil Karakas, Nadine Intering, M. Vat, Olivier Faivre, C. Harte, Salif Komi, Jimmy Ravier, Thibault Collin, Laure Coquoz, Icare Sakr, Edeny Baaklini, Sergio D. Hernandez-Charpak, Grégory Dumont, R. Buschman, Nicholas Buse, T. Denison, I. V. van Nes, L. Asboth, A. Watrin, L. Struber, F. Sauter-Starace, Lilia Langar, V. Auboiroux, S. Carda, S. Chabardès, T. Aksenova, Robin Demesmaeker, G. Charvet, J. Bloch, G. Courtine   +33 more
semanticscholar   +1 more source

Progression in translational research on spinal cord injury based on microenvironment imbalance

Bone Research, 2022
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level and imposes a considerable burden on patients, families, and society. Repair of the injured spinal cord has been recognized as a global medical challenge for many
Baoyou Fan, Zhijian Wei, S. Feng
semanticscholar   +1 more source

International Standards for Neurological Classification of Spinal Cord Injury: Revised 2019.

Topics in Spinal Cord Injury Rehabilitation, 2021
This booklet contains the eighth edition of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) that describes the examination (referred to as the International Standards examination) as well as the classification ...
R. Rupp, F. Biering-Sørensen, S. Burns, D. Graves, J. Guest, L. Jones, M. Read, G. Rodriguez, C. Schuld, Keith E Tansey-Md, K. Walden, S. Kirshblum   +11 more
semanticscholar   +1 more source

Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration

Journal of Neuroinflammation, 2021
Traumatic spinal cord injury (SCI) is a devastating neurological condition that results in a loss of motor and sensory function. Although extensive research to develop treatments for SCI has been performed, to date, none of these treatments have produced
Daniel J. Hellenbrand, Charlie Quinn, Zachariah J. Piper, Carolyn N. Morehouse, J. Fixel, Amgad S. Hanna   +5 more
semanticscholar   +1 more source

Rare case of real-time observation of paralytic deterioration after cervical dislocation in the hyperacute phase

BMC Musculoskeletal Disorders, 2022
Background There have been no prior reports of real-time detailed records leading to complete quadriplegia immediately after fracture dislocation in high-energy trauma. Here, we report a case of cervical dislocation in which the deterioration to complete
Tsutomu Endo, Kota Suda, Takafumi Fukui, Satoko Matsumoto, Miki Komatsu, Masahiro Ota, Chikara Ushiku, Junichi Yamane, Akio Minami, Masahiko Takahata, Norimasa Iwasaki   +10 more
doaj   +1 more source

Data-driven characterization of walking after a spinal cord injury using inertial sensors

Journal of NeuroEngineering and Rehabilitation, 2023
Background An incomplete spinal cord injury (SCI) refers to remaining sensorimotor function below the injury with the possibility for the patient to regain walking abilities.
Charlotte Werner, Meltem Gönel, Irina Lerch, Armin Curt, László Demkó   +4 more
doaj   +1 more source

Optimizing spinal cord injury care in Canada: Development of a framework for strategy and action

Frontiers in Public Health, 2022
National health strategies are integral in defining the vision and strategic direction for ensuring the health of a population or for a specific health area.
Joanna Marie B. Rivera, Charlene Yousefi, Christiana L. Cheng, Cameron D. Norman, Jeanne Legare, Alana McFarlane, Vanessa K. Noonan   +6 more
doaj   +1 more source

Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization

Cell & Bioscience, 2023
Background Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors and the polarization of infiltrating
Guangjin Gu, Bin Zhu, Jie Ren, Xiaomeng Song, Baoyou Fan, Han Ding, Jun Shang, Heng Wu, Junjin Li, Hongda Wang, Jinze Li, Zhijian Wei, Shiqing Feng   +12 more
doaj   +1 more source

Goal attainment in mobility after acute rehabilitation of mobility-restricting paralysis syndromes with regard to the ambulatory therapeutic level of participation NeuroMoves

BMC Neurology, 2021
Background A central goal of rehabilitation in patients with paralysis syndromes after stroke or spinal cord injury (SCI) is to restore independent mobility as a pedestrian or wheelchair user.
Andreas Hug, Tamara Spingler, Cornelia Hensel, Stefan Fichtner, Tiziana Daniel, Laura Heutehaus, Michel Wensing, Rüdiger Rupp, Norbert Weidner   +8 more
doaj   +1 more source