Results 131 to 140 of about 487,231 (316)

Counselling Patients with a Spinal Cord Injury

, 2007
The aim of this study was to improve current counselling services at the Auckland Spinal Unit. This purpose was achieved by co-researching the topic with people who have extensive experience of living in the community with a spinal cord injury to ...
Sliedrecht, Susan
core  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Modulation of Radiation – Induced tumor necrosis factor α (TNF-α) Gene Expression in the Rats Spinal Cord by Melatonin [PDF]

The spinal cord is the major dose- limiting organ for radiotherapy of cancer in the head and neck region. Understanding the cellular and molecular mechanisms may help to develop strategies to either increase the radiation tolerance or to treat spinal ...
رفاهی, سهیلا, شیرازی, علیرضا, حدادی, مریم, سپهری زاده, ضرغام, حدادی, غلامحسن   +4 more
core  

The prevalence of neuropathic pain after non-traumatic spinal cord lesion

, 2007
Study design: Retrospective register study. Objective: To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender ...
L Werhagen, Werhagen, L., Molander, Carl,, Hultling, C., C Hultling, C Molander   +5 more
core   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Intradural Bone Cement Leakage After Vertebroplasty, An Under-Recognized Potential Catastrophe: A Case Report

International Medical Case Reports Journal
Wensheng Liao,1,* Zhenxing Hou,2,* Yanzheng Gao1 1Department of Spine and Spinal Cord Surgery, Henan Provincial People’s Hospital, Zhengzhou, People’s Republic of China; 2Department of Spine and Spinal Cord Surgery, Henan University ...
Liao W, Hou Z, Gao Y
doaj  

Conus medullaris and cauda equina syndrome as complications of non-imaging guided epidural steroid injection: two case reports with comprehensive interdisciplinary work-up

BMC Neurology
Introduction Epidural steroid injection (ESI) is commonly performed in the outpatient setting for relieving lumbosacral radicular pain, i.e., sciatica. Neurological and neuro-urological adverse events are rare but devastating when occurring.
Oliver Gross, Kerstin Schweyer, Benjamin Fritz, Thomas M. Kessler, Martin Schubert, Armin Curt, Carl M. Zipser   +6 more
doaj   +1 more source

Cardiovascular response during urodynamics in individuals with spinal cord injury

, 2017
Study design: Retrospective chart review. Objectives: To establish the frequency and severity of autonomic dysreflexia (AD) during urodynamics among individuals with chronic spinal cord injury (SCI) and to investigate the possible effect of the number ...
Zhou, M-W, F Biering-Sørensen, Biering-Sorensen, F., Liu, N., M-W Zhou, Krassioukov, A. V., A V Krassioukov, Biering-Sørensen, F, N Liu, Krassioukov, A V, Liu, N   +10 more
core   +1 more source

Protein Disulfide Isomerase Disassembles TDP‐43/G3BP1 Condensates and Antagonizes TDP‐43 Pathological Aggregates

Advanced Science, EarlyView.
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu, Hao Liu, Yu‐Xuan Sun, Yuying Li, Xiangyi Liu, Li‐Qiang Wang, Zhaofei Yang, Qi Fu, Xiaojiao Xu, Jie Chen, Yingshuang Zhang, Jun Zhou, Weidong Le, Mengchao Cui, Yi Liang   +14 more
wiley   +1 more source

A great misfortune: second traumatic spinal cord injury

, 2002
Objective: A second and a separate traumatic spinal cord injury. which results in neurological deterioration, is very rare.
GENÇOSMANOGLU, B. E., GENCOSMANOGLU, BELGIN ERHAN, Kafadar, Ali Metin, M Hanci, Hanci, Mehmet Murat, A Kafadar, BE Gençosmanoğlu   +6 more
core   +1 more source