Results 161 to 170 of about 1,533,125 (359)

miR-NPs-RVG promote spinal cord injury repair: implications from spinal cord-derived microvascular endothelial cells

open access: yesJournal of Nanobiotechnology
Background Spinal cord injury (SCI) often leads to a loss of motor and sensory function. Axon regeneration and outgrowth are key events for functional recovery after spinal cord injury.
Chao Li   +11 more
doaj   +1 more source

Immune Checkpoint PD‐L1 Modulates Retinal Microglial Activation to Alleviate Vascular Leakage in Choroidal Neovascularization via ERK

open access: yesAdvanced Science, EarlyView.
PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou   +7 more
wiley   +1 more source

Convolutional Deep Operator Networks for Learning Nonlinear Focused Ultrasound Wave Propagation in Heterogeneous Spinal Cord Anatomy [PDF]

open access: yesarXiv
Focused ultrasound (FUS) therapy is a promising tool for optimally targeted treatment of spinal cord injuries (SCI), offering submillimeter precision to enhance blood flow at injury sites while minimizing impact on surrounding tissues. However, its efficacy is highly sensitive to the placement of the ultrasound source, as the spinal cord's complex ...
arxiv  

An Improved Approach for Contrast Enhancement of Spinal Cord Images based on Multiscale Retinex Algorithm [PDF]

open access: yesarXiv, 2014
This paper presents a new approach for contrast enhancement of spinal cord medical images based on multirate scheme incorporated into multiscale retinex algorithm. The proposed work here uses HSV color space, since HSV color space separates color details from intensity.
arxiv  

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu   +13 more
wiley   +1 more source

Non-Invasive Temporal Interference Electrical Stimulation for Spinal Cord Injury Rehabilitation: A Simulation Study [PDF]

open access: yesarXiv
Background: Spinal cord injury (SCI) rehabilitation remains a major clinical challenge, with limited treatment options for functional recovery. Temporal interference (TI) electrical stimulation has emerged as a promising non-invasive neuromodulation technique capable of delivering deep and targeted stimulation.
arxiv  

Simultaneous submicrometric 3D imaging of the micro-vascular network and the neuronal system in a mouse spinal cord [PDF]

open access: yesarXiv, 2014
Defaults in vascular (VN) and neuronal networks of spinal cord are responsible for serious neurodegenerative pathologies. Because of inadequate investigation tools, the lacking knowledge of the complete fine structure of VN and neuronal systems is a crucial problem.
arxiv  

Triple leads with longitudinal guarded cathodes in spinal cord stimulation-effect of transversal lead separation [PDF]

open access: yes, 2009
In spinal cord stimulation (SCS) clinical practice, longitudinal guarded cathode stimulation by a single lead, placed on the spinal cord midline provides the broadest parasthesia coverage.
Buitenweg, J.R.   +2 more
core   +1 more source

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