Results 11 to 20 of about 1,229,305 (356)

Walking naturally after spinal cord injury using a brain–spine interface

Nature, 2023
A reliable digital bridge restored communication between the brain and spinal cord and enabled natural walking in a participant with spinal cord injury. A spinal cord injury interrupts the communication between the brain and the region of the spinal cord
H. Lorach, Andrea Gálvez, Valeria Spagnolo, Félix Martel, Serpil Karakas, Nadine Intering, M. Vat, Olivier Faivre, C. Harte, Salif Komi, Jimmy Ravier, Thibault Collin, Laure Coquoz, Icare Sakr, Edeny Baaklini, Sergio D. Hernandez-Charpak, Grégory Dumont, R. Buschman, Nicholas Buse, T. Denison, I. V. van Nes, L. Asboth, A. Watrin, L. Struber, F. Sauter-Starace, L. Langar, V. Auboiroux, S. Carda, S. Chabardès, T. Aksenova, Robin Demesmaeker, G. Charvet, J. Bloch, G. Courtine   +33 more
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International Standards for Neurological Classification of Spinal Cord Injury: Revised 2019.

Topics in Spinal Cord Injury Rehabilitation, 2021
This booklet contains the eighth edition of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) that describes the examination (referred to as the International Standards examination) as well as the classification ...
R. Rupp, F. Biering-Sørensen, S. Burns, D. Graves, J. Guest, L. Jones, M. Read, G. Rodriguez, C. Schuld, Keith E Tansey-Md, K. Walden, S. Kirshblum   +11 more
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Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration

Journal of Neuroinflammation, 2021
Traumatic spinal cord injury (SCI) is a devastating neurological condition that results in a loss of motor and sensory function. Although extensive research to develop treatments for SCI has been performed, to date, none of these treatments have produced
Daniel J. Hellenbrand, Charlie Quinn, Zachariah J. Piper, Carolyn N. Morehouse, J. Fixel, Amgad S. Hanna   +5 more
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The PI3K/AKT signalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: Mechanisms and therapeutic opportunities

Cell Proliferation, 2022
Traumatic spinal cord injury (TSCI) causes neurological dysfunction below the injured segment of the spinal cord, which significantly impacts the quality of life in affected patients.
Xuegang He, Ying Li, Bo Deng, Ai-xin Lin, Guangzhi Zhang, Miao Ma, Yonggang Wang, Yong Yang, Xuewen Kang   +8 more
semanticscholar   +1 more source

Progression in translational research on spinal cord injury based on microenvironment imbalance

Bone Research, 2022
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level and imposes a considerable burden on patients, families, and society. Repair of the injured spinal cord has been recognized as a global medical challenge for many
Baoyou Fan, Zhijian Wei, S. Feng
semanticscholar   +1 more source

Production of human spinal-cord organoids recapitulating neural-tube morphogenesis

Nature Biomedical Engineering, 2022
Human spinal-cord-like tissues induced from human pluripotent stem cells are typically insufficiently mature and do not mimic the morphological features of neurulation. Here, we report a three-dimensional culture system and protocol for the production of
Ju-Hyun Lee, Hyogeun Shin, Mohammed R. Shaker, H. Kim, Si-Hyung Park, June Hoan Kim, Namwon Lee, Minjin Kang, S. Cho, Tae Hwan Kwak, Jong Woon Kim, Mi-Ryoung Song, Seunghwi Kwon, D. Han, Sanghyuk Lee, Se-Young Choi, I. Rhyu, H. Kim, D. Geum, Il‐Joo Cho, Woong Sun   +20 more
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Spinal Cord Stimulation

Definitions, 2020
A highly invasive form of electroanalgesia used to treat various chronic pain syndromes, which resist treatment by more common means. It is also used to treat peripheral ischemia, peripheral vascular disease, complex regional pain syndrome, intractable ...

semanticscholar   +1 more source

Overground walking patterns after chronic incomplete spinal cord injury show distinct response patterns to unloading

Journal of NeuroEngineering and Rehabilitation, 2018
Background Body weight support (BWS) is often provided to incomplete spinal cord injury (iSCI) patients during rehabilitation to enable gait training before full weight-bearing is recovered.
Christopher Schmidt Easthope, Luca Renato Traini, Lea Awai, Martina Franz, Georg Rauter, Armin Curt, Marc Bolliger   +6 more
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Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms

Frontiers in Neurology, 2019
Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial socioeconomic implications for patients and their care-givers. Recent advances in medical management of SCI has significantly improved diagnosis, stabilization,
Arsalan Alizadeh, Scott Dyck, Soheila Karimi-Abdolrezaee   +2 more
semanticscholar   +1 more source

Robotic body weight support enables safe stair negotiation in compliance with basic locomotor principles

Journal of NeuroEngineering and Rehabilitation, 2019
Background After a neurological injury, mobility focused rehabilitation programs intensively train walking on treadmills or overground. However, after discharge, quite a few patients are not able to independently negotiate stairs, a real-world task with ...
M. Bannwart, E. Rohland, C. A. Easthope, G. Rauter, M. Bolliger   +4 more
doaj   +1 more source