Results 201 to 210 of about 531,097 (305)
Advanced Science, EarlyView.This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li +9 more
wiley +1 more source
The Syndromes of the Arteries of the Brain and Spinal Cord [PDF]
, 1953 L. G. Kiloh
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Dimer‐Specific FokT‐seq Reveals DNA‐Binding Dimerization and Novel Genomic Targets of TDP‐43
Advanced Science, EarlyView.Loss of TDP‐43 dimerization is implicated in ALS, yet its mechanistic role remains elusive. This study introduces FokT, a novel system that restores TDP‐43 dimerization to map its DNA targets via FokT‐seq. The findings uncover key binding sites and offer a versatile tool for exploring dimer‐dependent transcriptional regulation.
Mingming Yang +4 more
wiley +1 more source
ON THE EPITHELIUM OF THE CENTRAL CANAL OF THE SPINAL CORD AND OF THE VENTRICLES OF THE BRAIN [PDF]
, 1879 Theodore Deecke
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Advanced Science, EarlyView.This schematic representation illustrates the interaction mechanisms between polyphenolic compounds and various materials (metals, proteins, polysaccharides, alkaloids, etc.). And explains the potential clinical application value of these materials (nanoparticles, coatings, films, capsules, and hydrogels constructed using polyphenols) in the fields of ...
Songwen Xue +6 more
wiley +1 more source
Advanced Science, EarlyView.SpaBatch is an end‐to‐end multi‐slice spatial transcriptomics data integration framework. It simultaneously performs embedding learning, spatial feature denoising and reconstruction, batch effect correction, and spatial domain optimization, effectively correcting batch effects and achieving accurate 3D spatial domain identification.
Jinyun Niu +5 more
wiley +1 more source
Advanced Image‐Guidance and Surgical‐Navigation Techniques for Real‐Time Visualized Surgery
Advanced Science, EarlyView.This review comprehensively summarizes advances in surgical navigation, covering both established and emerging intraoperative imaging technologies. It highlights mechanisms, advantages, limitations, and clinical applications, while emphasizing interdisciplinary collaboration.
Xiaoxiao Fan +9 more
wiley +1 more source
The Distribution of Paralysis and Anaesthesia in Injuries of the Cervical Region of the Spinal Cord [PDF]
, 1888 William Thorburn
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Advanced Science, EarlyView.This study presents a novel and facile thickness‐modulated 4D bioprinting approach using a smart bioink made of gelatin, GelMA, and MXene. Leveraging computational models, it creates living constructs with programmable unidirectional and bidirectional curvatures under a single UV exposure.
Jiahui Lai +7 more
wiley +1 more source