Results 31 to 40 of about 1,533,125 (359)

Correlation with basic differentiation processes of neurons [PDF]

, 1991
The development of the spinal cord involves the proliferation of neurons, their migration to well-defined areas, fiber outgrowth and synapse formation. The present study was designed to correlate the spatiotemporal pattern of expression of synaptophysin,
Altman, Angulo, Bööj, Cabalka, Chun, Dennis, Devoto, Hsu, Jahn, Jahn, Jahn, Kanemitsu, Kaplan, Knaus, Leclerc, Leube, Ley, Lizardi, Lupa, Mandler, Narayanan, Nornes, Nornes, Oppenheim, Phelps, Ritchie, Ruppert, Saito, Sarthy, Schilling, Stein, Südhof, Thomas, Vaughn, Vaughn, Vaughn, Vaughn, Xue   +37 more
core   +2 more sources

Effects of local hypothermia-rewarming on physiology, metabolism and inflammation of acutely injured human spinal cord. [PDF]

, 2020
In five patients with acute, severe thoracic traumatic spinal cord injuries (TSCIs), American spinal injuries association Impairment Scale (AIS) grades A-C, we induced cord hypothermia (33 °C) then rewarming (37 °C).
A Bricolo, A Mizuma, A Schubert, C Hochstim, DW Marion, GL Clifton, GV Varsos, HA Choi, I Phang, I Phang, JR Bethea, K Chatzipanteli, K Chatzipanteli, KL Carpenter, L Zhu, M Dididze, M Erecinska, MC Werndle, MC Werndle, MJ Gallagher, PE Batchelor, PJ Andrews, PJ Hutchinson, RR Hansebout, S Chen, S Saadoun, S Shibuya, SR Lewis, TP Lo Jr.   +28 more
core   +1 more source

Robotic body weight support enables safe stair negotiation in compliance with basic locomotor principles

Journal of NeuroEngineering and Rehabilitation, 2019
Background After a neurological injury, mobility focused rehabilitation programs intensively train walking on treadmills or overground. However, after discharge, quite a few patients are not able to independently negotiate stairs, a real-world task with ...
M. Bannwart, E. Rohland, C. A. Easthope, G. Rauter, M. Bolliger   +4 more
doaj   +1 more source

Overground walking patterns after chronic incomplete spinal cord injury show distinct response patterns to unloading

Journal of NeuroEngineering and Rehabilitation, 2018
Background Body weight support (BWS) is often provided to incomplete spinal cord injury (iSCI) patients during rehabilitation to enable gait training before full weight-bearing is recovered.
Christopher Schmidt Easthope, Luca Renato Traini, Lea Awai, Martina Franz, Georg Rauter, Armin Curt, Marc Bolliger   +6 more
doaj   +1 more source

Flumazenil therapy for a gabapentin-induced coma: a case report

Journal of Medical Case Reports, 2021
Background Spasticity and neuropathic pain are common in patients after spinal cord injury and negatively affect patients’ quality of life. Gabapentin and baclofen are frequently used to treat these conditions. We present a flumazenil-reversed gabapentin-
M. Masciullo, F. Pichiorri, G. Scivoletto, C. Foti, M. Molinari   +4 more
doaj   +1 more source

Towards contrast-agnostic soft segmentation of the spinal cord [PDF]

, 2023
Spinal cord segmentation is clinically relevant and is notably used to compute spinal cord cross-sectional area (CSA) for the diagnosis and monitoring of cord compression or neurodegenerative diseases such as multiple sclerosis. While several semi and automatic methods exist, one key limitation remains: the segmentation depends on the MRI contrast ...
arxiv   +1 more source

Comprehensive Monosynaptic Rabies Virus Mapping of Host Connectivity with Neural Progenitor Grafts after Spinal Cord Injury. [PDF]

, 2017
Neural progenitor cells grafted to sites of spinal cord injury have supported electrophysiological and functional recovery in several studies. Mechanisms associated with graft-related improvements in outcome appear dependent on functional synaptic ...
Adler, Andrew F, Kadoya, Ken, Kumamaru, Hiromi, Lee-Kubli, Corinne, Tuszynski, Mark H   +4 more
core   +2 more sources

Calibrated forceps model of spinal cord compression injury. [PDF]

, 2015
Compression injuries of the murine spinal cord are valuable animal models for the study of spinal cord injury (SCI) and spinal regenerative therapy.
Ariza, Jeanelle, Martínez-Cerdeño, Verónica, McDonough, Ashley, Monterrubio, Angela   +3 more
core   +2 more sources

Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury

Nature Communications, 2019
The role of microglia in spinal cord injury (SCI) remains poorly understood and is often confused with the response of macrophages. Here, we use specific transgenic mouse lines and depleting agents to understand the response of microglia after SCI.
V. Bellver-Landete, Floriane Bretheau, Benoit Mailhot, Nicolas Vallières, Martine Lessard, Marie-Ève Janelle, N. Vernoux, M. Tremblay, Tobias Fuehrmann, M. Shoichet, S. Lacroix   +10 more
semanticscholar   +1 more source

Opposite modulation of functional recovery following contusive spinal cord injury in mice with oligodendrocyte-selective deletions of Atf4 and Chop/Ddit3

Scientific Reports, 2023
The integrated stress response (ISR)-activated transcription factors ATF4 and CHOP/DDIT3 may regulate oligodendrocyte (OL) survival, tissue damage and functional impairment/recovery in white matter pathologies, including traumatic spinal cord injury (SCI)
Yonglin Gao, George Z. Wei, Michael D. Forston, Benjamin Rood, Emily R. Hodges, Darlene Burke, Kariena Andres, Johnny Morehouse, Christine Armstrong, Charles Glover, Lukasz P. Slomnicki, Jixiang Ding, Julia H. Chariker, Eric C. Rouchka, Sujata Saraswat Ohri, Scott R. Whittemore, Michal Hetman   +16 more
doaj   +1 more source