Results 91 to 100 of about 105,928 (348)

Subarachnoid Hemorrhage due to Ruptured Spinal Artery Aneurysm: A Diagnostic Challenge

Case Reports in Neurology, 2020
Subarachnoid hemorrhage (SAH) due to a solitary spinal aneurysm is extremely rare. Early diagnosis of spinal SAH is challenging, particularly when the spinal cord has not been compressed.
Ngoc Hoang Nguyen, Vien Chi Le, Trung Quoc Nguyen, Thang Huy Nguyen   +3 more
doaj   +1 more source

Identifying patients with malignant spinal cord compression (MSCC) near end of life who can benefit from palliative radiotherapy [PDF]

, 2022
Dirk Rades, Barbara Šegedin, Steven E. Schild, Darejan Lomidze, Theo Veninga, Jon Cacicedo   +5 more
openalex   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Pediatric non‐Hodgkin lymphoma as a rare cause of spinal cord injury: When lymphoma hides in the canal

Clinical Case Reports
Key Clinical Message Spinal cord compression from non‐Hodgkin lymphoma (NHL) should be considered as a potential diagnosis in cases of acute signs of myelopathy in pediatric patients.
Daniele Zama, Egidio Candela, Gennaro Pagano, Francesco Venturelli, Fraia Melchionda, Francesco Toni, Mino Zucchelli, Andrea Pession   +7 more
doaj   +1 more source

A case of cervicomedullary junction compression

Journal of Pediatric Critical Care, 2017
The C-V junction is a transition site between mobile cranium and relatively rigid spinal column. It is also the site of the medullo-spinal junction. CV anomalies are defects of development, not necessarily congenital and may not manifest at birth.
Ashok Gupta, Priyanshu Mathur, Manish Sharma, Vimesh Parmar   +3 more
doaj   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

A comparison of radiological descriptions of spinal cord compression with quantitative measures, and their role in non-specialist clinical management.

PLoS ONE, 2019
IntroductionMagnetic resonance imaging (MRI) is gold-standard for investigating Degenerative Cervical Myelopathy (DCM), a disabling disease triggered by compression of the spinal cord following degenerative changes of adjacent structures.
Jennifer Tempest-Mitchell, Bryn Hilton, Benjamin M Davies, Aria Nouri, Peter J Hutchinson, Daniel J Scoffings, Richard J Mannion, Rikin Trivedi, Ivan Timofeev, John R Crawford, Douglas Hay, Rodney J Laing, Mark R N Kotter   +12 more
doaj   +1 more source

Diffusion Tensor Imaging in a Large Longitudinal Series of Patients With Cervical Spondylotic Myelopathy Correlated With Long-Term Functional Outcome [PDF]

, 2018
BACKGROUND Fractional anisotropy (FA) of the high cervical cord correlates with upper limb function in acute cervical cord injury. We investigated the correlation between preoperative FA at the level of maximal compression and functional recovery in a ...
Budde, Matthew D., Kaushal, Mayank, Kurpad, Shekar N., Motovylyak, Olesya, Rao, Avinash, Schmit, Brian D., Soliman, Hesham, Vedantam, Aditya, Wang, Marjorie C.   +8 more
core   +1 more source