Results 91 to 100 of about 950,644 (300)

Secondary changes in spinal cord due to prolonged compression at trauma of cervical spine

Ukrainian Neurosurgical Journal, 2013
Introduction. One of the reasons for secondary changes in spinal cord at spinal trauma — is it’s tissue alteration by vertebrae bone fragments and dura mater.
Vitaliy Tsymbaliuk, Waldemar Nevodnik, Mykola Salkov   +2 more
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

Inhibitory postsynaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated frog spinal cord [PDF]

, 1975
The actions of glycine, GABA, α-alanine, β-alanine and taurine were studied by intracellular recordings from lumbar motoneurons of the isolated spinal cord of the frog.
Krumnikl, J., M. Linder, Lucia Schindler, J. Krumnikl, Linder, M., P. Grafe, Schindler, Lucia, Sonnhof, U., Grafe, Peter, U. Sonnhof   +9 more
core   +1 more source

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

The Spinal Cord

, 2009
Many hundreds of thousands suffer spinal cord injuries leading to loss of sensation and motor function in the body below the point of injury. Spinal cord research has made some significant strides towards new treatment methods, and is a focus of many ...
Watson C., Paxinos G., Kayalioglu G.
core   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Miniaturized Multifunctional Valves for Intelligent Pneumatic Systems in Soft Robotics

Advanced Intelligent Systems, EarlyView.
Miniaturized multifunctional pneumatic valves in normally closed (NC) and normally open (NO) configurations enable reconfigurable and programmable fluidic logic—including AND, OR, NAND, and NOR gates—with/without physical replumbing. These valves integrate sensing, logic, and actuation within a unified architecture, demonstrated through an electronics ...
J. Xu, X. Z. Niu, J. Andersson, D./G. Broo, K. Hjort   +4 more
wiley   +1 more source

Pain management following new and long-standing spinal cord injury: A pilot study of changes in pain intensity experienced during the day [PDF]

, 2013
The aim of the study was to examine variations in pain intensity during the day experienced by patients with spinal cord injury. Fourteen consecutive patients had clinical and demographic data recorded.
Frank, AO, Gawronski, J, Spyridonis, F, Ghinea, G   +3 more
core   +1 more source

Magnetic Resonance Imaging Preprocessing for Robust Spinal Cord Segmentation in Cervical Myelopathy

Journal of Imaging
Accurate spinal cord segmentation is important for quantitative analysis of spinal cord magnetic resonance imaging, including measurement of cross-sectional area and diffusion-based microstructural characterization.
Hediyeh Toufani, Richard M. Dansereau, Philippe Phan, Jefferson R. Wilson, Eve C. Tsai   +4 more
doaj   +1 more source