Results 121 to 130 of about 416,929 (394)

Secondary changes in spinal cord due to prolonged compression at trauma of cervical spine

Ukrainian Neurosurgical Journal, 2013
Introduction. One of the reasons for secondary changes in spinal cord at spinal trauma — is it’s tissue alteration by vertebrae bone fragments and dura mater.
Vitaliy Tsymbaliuk, Waldemar Nevodnik, Mykola Salkov   +2 more
doaj   +1 more source

Comparison of medical and surgical treatment for acute cervical compressive hydrated nucleus pulposus extrusion in dogs [PDF]

, 2017
Although successful outcomes have been reported after medical and surgical treatment for dogs with cervical hydrated nucleus pulposus extrusion (HNPE), it is unknown which treatment option is preferred.
Beltran, Cardy, Crawford, da Costa, De Decker, De Decker, De Risio, De Risio, Dolera, Falzone, Fardon, Fenn, Hamilton, Hillman, Jeffery, Kamishina, Konar, Lowrie, Manunta, Olby, Royaux, Sharp, Smolders, Yousefifard   +23 more
core   +1 more source

Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model

Advanced Science, EarlyView.
Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis, Elena Capitanini, Karen Kira, Claudia Dell'Amico, Jun Takahashi, Marco Onorati, Fabian Raudzus, Vittoria Raffa   +7 more
wiley   +1 more source

Spinal cord compression secondary to brown tumour in a patient on long-term haemodialysis: a case report. [PDF]

, 2009
Brown tumours may occur secondary to hyperparathyroidism in patients with chronic renal failure (CRF). Diagnosing a spinal brown tumour causing cord compression requires a high index of suspicion.
Luk, KD, Mak, KC, Wong, YW
core   +1 more source

The Prevalence and Phenotype of Activated Microglia/Macrophages within the Spinal Cord of the Hyperostotic Mouse (twy/twy) Changes in Response to Chronic Progressive Spinal Cord Compression: Implications for Human Cervical Compressive Myelopathy

PLoS ONE, 2013
Background Cervical compressive myelopathy, e.g. due to spondylosis or ossification of the posterior longitudinal ligament is a common cause of spinal cord dysfunction.
T. Hirai, K. Uchida, H. Nakajima, A. Guerrero, N. Takeura, Shuji Watanabe, Daisuke Sugita, Ai Yoshida, W. Johnson, H. Baba   +9 more
semanticscholar   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Intraoperative ultrasonography of the vertebral canal in dogs

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2015
Intraoperative ultrasound (IOS) can provide details on various conditions of the spinal cord and vertebral canal. The aim of the present study was to evaluate the feasibility of using IOS in dogs undergoing spinal surgery and to describe the main ...
M.A. Bonelli, E.A. Tudury, C.R.O. Santos, B.M. Araújo, C.C. Diogo, A.C. Silva, F.S. Costa   +6 more
doaj   +1 more source

Multiclass Spinal Cord Tumor Segmentation on MRI with Deep Learning [PDF]

arXiv, 2020
Spinal cord tumors lead to neurological morbidity and mortality. Being able to obtain morphometric quantification (size, location, growth rate) of the tumor, edema, and cavity can result in improved monitoring and treatment planning. Such quantification requires the segmentation of these structures into three separate classes.
arxiv  

Surgical decompression improves recovery from neurological deficit and may provide a survival benefit in patients with diffuse large B-cell lymphoma-associated spinal cord compression: a case-series study

World Journal of Surgical Oncology, 2013
BackgroundMalignancy-associated spinal cord compression is generally treated by surgical decompression, radiotherapy or a combination of both. Since diffuse large B-cell lymphoma (DLBCL) is highly sensitive to both chemotherapy and radiotherapy, the role
Ching-Ming Chang, Hung-Chieh Chen, Youngsen Yang, Ren‐Ching Wang, W. Hwang, C. Teng   +5 more
semanticscholar   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source