ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao+6 more
wiley +1 more source
Solitary thoracic spine osteochondroma: a rare cause for spinal cord compression. [PDF]
Gader G+4 more
europepmc +1 more source
Spinal MRI in Patients with Suspected Metastatic Spinal Cord Compression: A Quality Improvement Audit in a District General Hospital in Kent, UK. [PDF]
Bachour ME+13 more
europepmc +1 more source
Abstract Background Hereditary spastic paraplegias (HSP) are rare disorders sharing common features of leg spasticity with gait impairment. Simple and complex forms are recognized; over 50% of cases remain unsolved genetically. Little is known about the genetics of HSP among Indigenous Peoples. Objectives To describe clinical, radiological, and genetic
Ekhlas Assaedi+7 more
wiley +1 more source
Cerebrospinal fluid pressure dynamics as a biomechanical marker for quantification of spinal cord compression: Conceptual framework and systematic review of clinical trials. [PDF]
Kheram N+12 more
europepmc +1 more source
Video Urodynamic Study in Patients with Parkinson's Disease and Multiple System Atrophy
Abstract Background Most studies have analyzed the urodynamic characteristics of patients with Parkinson's disease (PD) and multiple system atrophy (MSA) using conventional urodynamic studies. Objectives This study investigated the urodynamic characteristics of both diseases using video urodynamic study (VUDS).
Hyun Sik Yoon+3 more
wiley +1 more source
Hybrid Therapy with SBRT Target-Tailored Tumor Resection for High-Grade Metastatic Epidural Spinal Cord Compression (MESCC): Illustrative Case. [PDF]
De Robertis M+10 more
europepmc +1 more source
Movement Disorders in Neuromyelitis Optica Spectrum Disorder: A Systematic Review
Abstract Background Several movement disorders (MD) have been reported to occur in neuromyelitis optica spectrum disorder (NMOSD). No extensive review has addressed the whole spectrum of MD in NMOSD. Objective This article aims to review MD in NMOSD, describing its prevalence and features.
Luciana A.F. Bringel+18 more
wiley +1 more source
Management of multiple myeloma presenting as malignant spinal cord compression during pregnancy: a case report. [PDF]
Mullanfiroze K+8 more
europepmc +1 more source
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin+8 more
wiley +1 more source