Results 201 to 210 of about 950,644 (300)

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

A Case of Metastatic Spinal Cord Compression in a Patient With Coexisting Chronic Lymphocytic Leukemia and Colon Cancer. [PDF]

Cureus
Abbas K, Nagumantry S.
europepmc   +1 more source

An Ergonomic Customizable Soft Robotic Glove Toward Personalized Hand Rehabilitation

SmartBot, EarlyView.
Soft robotic gloves for hand rehabilitation are often limited by poor fit and uneven pressure on the fingers. Here, the authors report an ergonomic all‐fabric glove whose dual‐action actuators are tailored to individual finger geometry by CNC heat sealing, with symmetrical chambers that distribute interface pressure more evenly. Weighing only 90 g, the
Rui Chen, Firman Isma Serdana, Domenico Chiaradia, Xianlong Mai, Elena Losanno, Gabriele Righi, Claudia De Santis, Federica Serra, Vincent Mendez, Cristian Camardella, Daniele Leonardis, Giulio Del Popolo, Silvestro Micera, Antonio Frisoli   +13 more
wiley   +1 more source

Early Neurological Improvement and Ambulation Recovery After Delayed Surgery in Surgically Selected Nonambulatory Metastatic Epidural Spinal Cord Compression: A Retrospective Cohort Study. [PDF]

Curr Oncol
Baydar AT, Taskala B, Topal B, Bayindir M, Batman YE, Yilmaz I, Dalgic A.   +6 more
europepmc   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Automated Detection of Cervical Spinal Cord Compression on MRI Using YOLO11 Deep Learning Architecture: A Two-Center External Validation Study. [PDF]

Spine (Phila Pa 1976)
Du Q, Kong W, Chang Y, Xin Z, Shao X, Feng L, Zhou J, Zhang Y, Li X, Cao G, Fu R, Wa Q, Zhou Z.   +12 more
europepmc   +1 more source

Laponite Network Controls FGF‐2 Release and Drives Functional Nerve Regeneration via 3D‐Printed Nerve Wrap Interfaces

Small Methods, EarlyView.
We developed a 3D‐printed nerve interface integrating a biomimetic nanocomposite hydrogel with sustained delivery of thermostable FGF‐2. The bioactive interface supports Schwann cell activity and myelination while providing a regenerative microenvironment.
Diego N. Rodriguez‐Sanchez, Akshat Joshi, Saeed Safari, Leticia A. M. de Carvalho, Kevin S. Muller, Uijin Kim, Luciana P. Cartarozzi, Meenakshi Kamaraj, Menekse Ermis, Natan R. de Barros, Alexandre L. R. de Oliveira   +10 more
wiley   +1 more source

Advancements in metastatic spinal cord compression treatment: a narrative review of innovations, challenges, and future directions. [PDF]

Ann Med Surg (Lond)
Patel T, Henna F, Sharif I, Noor A, Siddiqui HT, Barkat-Ullah Z, Ishaque M, Ali Khan N, Hanani C, Goyal A, Anand N.   +10 more
europepmc   +1 more source

Recent Advances in Oriented Hydrogels: From Fundamental Mechanisms to Future Challenges

SusMat, EarlyView.
Traditional hydrogels suffer from weak mechanical properties and limited functionality due to their random polymer networks. This review comprehensively summarizes the reinforcement mechanisms of oriented structure for hydrogels, the design/fabrication strategies, and the latest application progress of high‐strength oriented hydrogels.
Chang Xu, Xijing Zhuang
wiley   +1 more source

Long-Term Results of a Comparison Between 15 × 2.633 Gy and 20 × 2.0 Gy for Malignant Spinal Cord Compression in Patients with Longer Expected Survival Times. [PDF]

J Clin Med
Rades D, Staackmann C, Lomidze D, Segedin B, Groselj B, Lopez Campos F, Navarro-Martin A, Cacicedo J.   +7 more
europepmc   +1 more source