Results 291 to 300 of about 382,326 (389)
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger +1 more
wiley +1 more source
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Exploring the Potential of a Deep Learning Model for Early CT Detection of High-Grade Metastatic Epidural Spinal Cord Compression and Its Impact on Treatment Delays. [PDF]
Hallinan JTPD +17 more
europepmc +1 more source
ABSTRACT Purpose Pediatric craniofacial imaging may involve examination of both the skull and brain tissues via CT and MRI, respectively. DREAMER (Dual Repetition and Echo Acquisition with Multi‐contrast Encoding and Reconstruction) simultaneously acquires solid‐ and soft‐tissue images, potentially providing a rapid, high‐resolution, and radiation‐free
Brian‐Tinh Duc Vu +8 more
wiley +1 more source
Spinal Cord Compression As the Initial Manifestation of Relapsed Acute Myeloid Leukemia: A Case Report and Literature Review of a Rare Presentation. [PDF]
Gregg-Garcia R, Sayar H.
europepmc +1 more source
Detrusor Overactivity and Urodynamics
ABSTRACT While overactive bladder (OAB) is a clinical diagnosis, detrusor overactivity is identified through urodynamic testing. UDS is usually considered when primary treatment for OAB fails, because UDS is expensive, time consuming, invasive, and sometimes inaccurate, and it is not considered to influence treatment strategy substantially.
Laura N. Nguyen, Geneviève Nadeau
wiley +1 more source
Microscopically-assisted Uninstrumented Surgical Tumor Decompression as an alternative to open surgery for symptomatic metastatic epidural spinal cord compression. [PDF]
Harvie CE +5 more
europepmc +1 more source
ABSTRACT The International Soft‐Tissue Sarcoma Consortium (INSTRuCT) was established as a global partnership among various pediatric soft tissue sarcoma groups, including the Children's Oncology Group (COG), European Pediatric Soft Tissue Sarcoma Group (EpSSG), and Cooperative Weichteilsarkom Studiengruppe (CWS). One of INSTRuCT's primary objectives is
Andreas Schmidt +8 more
wiley +1 more source

