Results 61 to 70 of about 382,326 (389)

Omega-3 Fatty Acids Improve Recovery, whereas Omega-6 Fatty Acids Worsen Outcome, after Spinal Cord Injury in the Adult Rat [PDF]

, 2006
Spinal cord injury (SCI) is a cause of major neurological disability, and no satisfactory treatment is currently available. Evidence suggests that polyunsaturated fatty acids (PUFAs) could target some of the pathological mechanisms that underlie damage ...
Curran, O. E., Dyall, Simon, Huang, W. L., King, V. R., Michael-Titus, A. T., Priestley, J. V.   +5 more
core   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Contemporary treatment with radiosurgery for spine metastasis and spinal cord compression in 2015

Radiation Oncology Journal, 2015
With the progress of image-guided localization, body immobilization system, and computerized delivery of intensity-modulated radiation delivery, it became possible to perform spine radiosurgery.
S. Ryu, H. Yoon, A. Stessin, Fred Gutman, A. Rosiello, Raphael P. Davis   +5 more
semanticscholar   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury

Neural Regeneration Research, 2023
Chronic compressive spinal cord injury in compressive cervical myelopathy conditions can lead to rapid neurological deterioration in the early phase, followed by partial self-recovery, and ultimately an equilibrium state of neurological dysfunction ...
Zhengran Yu, Xing Cheng, Wenxu Pan, Cheng Yu, Yang Duan   +4 more
doaj   +1 more source

Clinical and Radiological Parameters Predict Functional Improvement following Surgical Intervention [PDF]

, 2020
Cervical spondylotic myelopathy (CSM), defined as "compression of the spinal cord in the cervical area of the spine", which ranges widely in severity and mechanism.
Sheehan, Erin
core  

A validation of the Oswestry Spinal Risk Index [PDF]

, 2016
Purpose The purpose of this study was to validate the Oswestry Spinal Risk Index (OSRI) in an external population. The OSRI predicts survival in patients with metastatic spinal cord compression (MSCC).
A Leithner, A. Tambe, B Balain, C Wibmer, CS Lee, DA Karnofsky, HC Bauer, I Laufer, Irfan Siddique, J. Gregory, J. Stephenson, K Tomita, Mohammad Saeed, NA Quraishi, P Paholpak, PS Rose, R. Verma, S Yang, S. Whitehouse, V. Sinclair, Y Tokuhashi, Y Tokuhashi   +21 more
core   +1 more source

Malignant Spinal Cord Compression

Journal of the Royal College of Physicians of Edinburgh, 2019
Malignant spinal cord compression (MSCC) is a potentially devastating consequence of cancer. Early recognition of the signs and symptoms of MSCC can allow diagnosis prior to the development of irreversible complications. Information provision to patients and doctors regarding the risk of MSCC and a streamlined pathway for further investigation are ...
A. Graham Macdonald, Ian Garbett, Nauzan Nazeer, Daniel Lynch   +3 more
openaire   +2 more sources

Cold Atmospheric Plasma Selectively Disrupts Breast Cancer Growth in a Bioprinted 3D Tumor‐Stroma Co‐Culture Model

Advanced Healthcare Materials, EarlyView.
This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret, Jean‐Baptiste Billeau, Michael H. Weber, Derek H. Rosenzweig, Stephan Reuter   +4 more
wiley   +1 more source

Battery‐Free Dual‐Channel Wireless Neurostimulator Using Passive Circuitry for Neuropathic Pain Modulation

Advanced Healthcare Materials, EarlyView.
A compact, wireless neural stimulator featuring a novel tapping inductor enables selective and independent stimulation of the motor cortex in rats via a single receiver coil. This minimally invasive system effectively reduces neuropathic pain through targeted cortical activation, offering a new avenue for bioelectronic pain therapies and advancing ...
Jeongju Moon, Kyungmo Seong, Hyeon Gyu Kim, Wonki Mun, Seung Hyun Min, Sung‐Yun Park, Joonsoo Jeong, Chin Su Koh, Hyun Ho Jung, Kyungsik Eom   +9 more
wiley   +1 more source