Results 141 to 150 of about 325,167 (345)

Early exposure to environmental toxin contributes to neuronal vulnerability and axonal pathology in a model of familial ALS [PDF]

, 2011
Adult onset amyotrophic lateral sclerosis (ALS) arises due to progressive and irreversible functional deficits to the central nervous system, specifically the loss of motor neurons.
Christopher A. Shaw, Grace Lee
core   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Interaction between increasing body mass index and spinal cord injury to the probability of developing a diagnosis of nonalcoholic fatty liver disease

, 2022
Dan Eisenberg, Katherine Arnow, Nicolas B. Barreto, Kristen Davis, Sherri L. LaVela, Susan M. Frayne, Andrea Nevedal, Justina Wu, Alex H. S. Harris   +8 more
openalex   +1 more source

Letter to the Editor: Traumatic Spinal Cord Injury and Risk of Early and Late Onset Alzheimer's Disease and related Dementia: Large Longitudinal Study [PDF]

, 2021
Elham Mahmoudi, Paul Lin, Mark D. Peterson, Michelle A. Meade, Denise G. Tate, Neil Kamdar   +5 more
openalex   +1 more source

Spinal Cord Diseases [PDF]

Journal of Neuropathology and Experimental Neurology, 1966
openaire   +2 more sources

Reliable AI Platform for Monitoring BCI Caused Brain Injury and Providing Real‐Time Protection

Advanced Science, EarlyView.
BrainGuard enables real‐time and interpretable assessment of brain injury caused by brain computer interface (BCI). Using feature‐based Gaussian process (GP) emulators trained on limited biomechanical data, it efficiently predicts full‐field strain and constructs patient‐specific digital brain twins to support clinical diagnosis and long‐term BCI ...
Chufan He, Yanjun Ding, Timon Rabczuk, Chensen Ding   +3 more
wiley   +1 more source

Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury

Neural Regeneration Research
The inflammatory microenvironment and neurotoxicity can hinder neuronal regeneration and functional recovery after spinal cord injury. Ruxolitinib, a JAK-STAT inhibitor, exhibits effectiveness in autoimmune diseases, arthritis, and managing inflammatory ...
Jiang Cao, Xiao Yu, Jingcheng Liu, Jiaju Fu, Binyu Wang, Chaoqin Wu, Sheng Zhang, Hongtao Chen, Zi Wang, Yinyang Xu, Tao Sui, Jie Chang, Xiaojian Cao   +12 more
doaj   +1 more source

Clinical applications of diffusion tensor tractography of the spinal cord [PDF]

, 2018
Diffusion tensor imaging (DTI) can visualize the white matter tracts in vivo. The aim of this study was to assess the clinical utility of DTI in patients with diseases of the spinal cord.
Becker, Christoph, Delavelle, Jacqueline, Jlassi, Helmi, Lövblad, Karl-Olof, Rilliet, Bénédict, Vargas, Maria, Viallon, Magalie   +6 more
core  

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Spinal Cord Stimulation in Heart Failure: Effect on Disease-Associated Biomarkers [PDF]

, 2017
Jan Naar, Deborah A. Jaye, Cecilia Linde, Petr Neužil, Petr Doškář, Filip Málek, Frieder Braunschweig, Lars H. Lund, Lars Mortensen, Magnus Bäck, Bengt Linderoth, Göran Lind, Fred Kueffer, Jodi Koehler, Kambiz Shahgaldi, Marcus Ståhlberg   +15 more
openalex   +1 more source