Results 141 to 150 of about 305,172 (361)

Neuroprotective effect of adult hematopoietic stem cells in a mouse model of motoneuron degeneration

open access: yesNeurobiology of Disease, 2007
Degenerative spinal motor diseases, like amyotrophic lateral sclerosis, are produced by progressive degeneration of motoneurons. Their clinical manifestations include a progressive muscular weakness and atrophy, which lead to paralysis and premature ...
Carmen Cabanes   +3 more
doaj  

Dynamic MR angiography (MRA) of spinal vascular diseases at 3T [PDF]

open access: yes, 2018
Spinal magnetic resonance angiography (MRA) is difficult to perform because of the size of the spinal cord vessels. High-field MR improves resolution and imaging speed.
Kulcsár, Zolt   +7 more
core  

Clinical and Radiological Parameters Predict Functional Improvement following Surgical Intervention [PDF]

open access: yes, 2020
Cervical spondylotic myelopathy (CSM), defined as "compression of the spinal cord in the cervical area of the spine", which ranges widely in severity and mechanism.
Sheehan, Erin
core  

Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading

open access: yesAdvanced Science, EarlyView.
Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li   +16 more
wiley   +1 more source

Dual-directional regulation of spinal cord injury and the gut microbiota

open access: yesNeural Regeneration Research
There is increasing evidence that the gut microbiota affects the incidence and progression of central nervous system diseases via the brain-gut axis.
Yinjie Cui   +9 more
doaj   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

open access: yesAdvanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He   +11 more
wiley   +1 more source

Postmortem diffusion MRI of the entire human spinal cord at microscopic resolution

open access: yesNeuroImage: Clinical, 2018
The human spinal cord is a central nervous system structure that plays an important role in normal motor and sensory function, and can be affected by many debilitating neurologic diseases. Due to its clinical importance, the spinal cord is frequently the
Evan Calabrese   +6 more
doaj  

Enhancing Grasping Function with a Thermoresponsive Ionogel Adhesive Glove for Patients with Rheumatic Diseases

open access: yesAdvanced Science, EarlyView.
This study presents a novel portable grasp‐assist glove, weighing only 47 g. The glove integrates smart adhesive pads and a hands‐free control interface based on IMU, designed to aid rheumatic patients with impaired hand function. The system enables switchable adhesion with independent control and detection of user release intent.
Shiqiang Wang   +11 more
wiley   +1 more source

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